Study of INS50589 Intravenous Infusion in Subjects Undergoing Coronary Artery Bypass Grafting (CABG) Involving Cardiopulmonary Bypass



Status:Terminated
Conditions:Peripheral Vascular Disease, Cardiology
Therapuetic Areas:Cardiology / Vascular Diseases
Healthy:No
Age Range:18 - 75
Updated:11/19/2016
Start Date:April 2006

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Randomized, Multicenter, Placebo-Controlled, Double-Blind, Parallel Group Study of INS50589 Intravenous Infusion in Subjects Undergoing Coronary Artery Bypass Graft Surgery Involving Cardiopulmonary Bypass

The purpose of this trial is to identify a dose or doses of INS50589 intravenous infusion
that are well-tolerated and which reduce postoperative bleeding and blood product
transfusion.


Inclusion Criteria:

- Are scheduled for primary CABG by median sternotomy involving cardiopulmonary bypass

- Willing to receive allogeneic blood product transfusions during and after surgery

Exclusion Criteria:

- Have had previous cardiac surgery

- Have had previous median sternotomy

- Have tendency for bleeding or family history of bleeding

- Have an abnormally low platelet count

- Have received certain anticoagulant or antiplatelet medications within a specified
time period prior to the scheduled CABG surgery
We found this trial at
27
sites
Greenville, North Carolina 27834
1139
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Greenville, NC
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Birmingham, Alabama 35211
682
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Birmingham, AL
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Birmingham, Alabama 35211
682
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Birmingham, AL
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Cincinnati, Ohio 45242
734
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Cincinnati, OH
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Cincinnati, Ohio 45220
725
mi
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Cincinnati, OH
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730
mi
from
Cincinnati, OH
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2301 Erwin Rd
Durham, North Carolina 27710
919-684-8111
Duke Univ Med Ctr As a world-class academic and health care system, Duke Medicine strives...
1052
mi
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Durham, NC
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7950 West Jefferson Boulevard
Fort Wayne, Indiana 48804
707
mi
from
Fort Wayne, IN
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Houston, Texas 77030
572
mi
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Houston, TX
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Jackson, Tennessee 38305
518
mi
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Jackson, TN
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Jackson, Tennessee 38301
520
mi
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Jackson, TN
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725
mi
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Lexington, KY
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Lexington, Kentucky 40506
725
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Lexington, KY
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Nashville, Tennessee 37203
618
mi
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Nashville, TN
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Oklahoma City, Oklahoma 73120
150
mi
from
Oklahoma City, OK
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Oklahoma City, Oklahoma 73120
150
mi
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Oklahoma City, OK
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Oklahoma City, Oklahoma 73109
160
mi
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Oklahoma City, OK
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Rochester, New York 14621
1124
mi
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Rochester, NY
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Saginaw, Michigan 48601
826
mi
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Saginaw, MI
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Saginaw, Michigan 48602
824
mi
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Saginaw, MI
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7901 Frost Street
San Diego, California 92123
858-939-3400
Sharp Memorial Hospital Sharp Memorial Hospital offers clinical excellence with the latest technology and patient-centered...
1139
mi
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San Diego, CA
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801 N Rutledge St
Springfield, Illinois 62702
(217) 545-8000
Southern Illinois University School of Medicine At SIU School of Medicine, research includes biologically oriented...
462
mi
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Springfield, IL
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Springfield, Illinois 62701
462
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Springfield, IL
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701 N 1st St
Springfield, Illinois 62781
(217) 788-3000
Memorial Medical Center Memorial Medical Center is a Magnet-designated, acute care hospital in Springfield that...
462
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Springfield, IL
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1408
mi
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Tacoma, WA
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Tacoma, Washington 98405
1408
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Tacoma, WA
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Winchester, Virginia 22604
1065
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Winchester, VA
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