Biomarker Study in Participants With Migraine

Inclusion Criteria:

- Participants with migraine who have previously participated in study NTC02163993 and
received one of the selected doses of galcanezumab or placebo

- Have suitable skin characteristics for the dermal capsaicin challenge

Exclusion Criteria:

- Have a history of significant allergies, in particular to ethanol or sensitivity to
the fruits of capsicum plants (for example, chili peppers)

- Have eczema, scleroderma, psoriasis, dermatitis, keloids, tumors, ulcers, burns,
flaps, or grafts on their forearm or other abnormality of the skin which may interfere
with the study assessments

- Cannot avoid excess tanning (any exposure to sunlight or a tanning bed which would
cause a sunburn reaction) throughout the study and cannot cover forearms for 24 hours
prior to each treatment period

- Have excessive hair growth on the volar surface of the forearm or participants
currently using lotions, oils, depilatory preparations, or other topical treatments on
a regular basis which cannot be discontinued for the duration of the study; has used
any topical treatments within 7 days of the start of the study