Evaluation of Cardiac Function With Cardio-respiratory Synchronized MRI
| Status: | Recruiting |
|---|---|
| Conditions: | Peripheral Vascular Disease, Cardiology |
| Therapuetic Areas: | Cardiology / Vascular Diseases |
| Healthy: | No |
| Age Range: | 7 - 95 |
| Updated: | 4/17/2018 |
| Start Date: | March 29, 2018 |
| End Date: | December 2018 |
| Contact: | Gabrielle Maranga |
| Email: | Gabrielle.Maranga@nyumc.org |
| Phone: | 212 263 6248 |
The purpose of this investigation is to evaluate newer methods of performing cardiovascular
MRI (CMR) that will provide new kinds of information related to the interplay between the
cardiac and the respiratory cycles, such as the interaction between the left ventricle and
the right ventricle during respiration . The primary statistical objective is to provide
preliminary indications of the relative utility of the investigational imaging software in
terms of image quality and suitability for routine clinical use. Image quality will be
expressed in terms of signal-to-noise ratios (SNR), contrast-to-noise ratios (CNR) and
subjective Likert-type qualitative assessments independently provided by each of multiple
blinded readers for each image. Suitability for routine use will be assessed in terms of
imaging time and a binary indicator of whether, in the opinion of the investigator, adverse
procedural complications (not expected) were encountered during a given imaging session.
MRI (CMR) that will provide new kinds of information related to the interplay between the
cardiac and the respiratory cycles, such as the interaction between the left ventricle and
the right ventricle during respiration . The primary statistical objective is to provide
preliminary indications of the relative utility of the investigational imaging software in
terms of image quality and suitability for routine clinical use. Image quality will be
expressed in terms of signal-to-noise ratios (SNR), contrast-to-noise ratios (CNR) and
subjective Likert-type qualitative assessments independently provided by each of multiple
blinded readers for each image. Suitability for routine use will be assessed in terms of
imaging time and a binary indicator of whether, in the opinion of the investigator, adverse
procedural complications (not expected) were encountered during a given imaging session.
Inclusion Criteria:
- Subjects will be selected as they are scheduled for clinical MR examinations.
- Subjects will be selected on the basis of their willingness and ability to
participate, on their comprehension of the informed consent document, on their
likelihood of completing the study, and on the clinical appropriateness of the
investigational technique for a given patient.
Exclusion Criteria:
- electrical implants such as cardiac pacemakers or perfusion pumps
- ferromagnetic implants such as aneurysm clips, surgical clips, prostheses, artificial
hearts, valves with steel parts, metal fragments, shrapnel, tattoos near the eye, or
steel implants
- ferromagnetic objects such as jewelry or metal clips in clothing
- pre-existing medical conditions including a likelihood of developing seizures or
claustrophobic reactions, and any greater than normal potential for cardiac arrest.
We found this trial at
1
site
550 1st Ave
New York, New York 10016
New York, New York 10016
(212) 263-7300
Principal Investigator: Leon Axel, MD
New York University School of Medicine NYU School of Medicine has a proud history that...
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