Comparison Trial of Letrozole to Anastrozole in the Adjuvant Treatment of Postmenopausal Women With Hormone Receptor and Node Positive Breast Cancer



Status:Completed
Conditions:Breast Cancer, Cancer
Therapuetic Areas:Oncology
Healthy:No
Age Range:33 - 96
Updated:4/21/2016
Start Date:December 2005
End Date:September 2014

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Eligible patients will be post-menopausal hormone receptor- and lymph node-positive females
who recently underwent primary surgery for breast cancer. Patients will be randomized to
letrozole (2.5 mg per day for 5 years) vs anastrozole (1 mg per day for 5 years). Follow up
will occur for 5 years after the completion of enrollment for survival and disease status
updates.


Inclusion Criteria:

- Recent primary surgery for breast cancer

- Early stage breast cancer

- Postmenopausal

- Hormone receptor positive

- Positive lymph node involvement

Exclusion Criteria:

- Metastatic disease

- Presence of contralateral breast cancer including DCIS

- Progression

Other protocol-defined inclusion/exclusion criteria may apply.
We found this trial at
42
sites
Ocoee, Florida 34761
1133
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Ocoee, FL
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1099 5th Avenue North
St. Petersburg, Florida 33705
1116
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St. Petersburg, FL
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842
mi
from
Athens, GA
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Bedford, Texas 76022
342
mi
from
Bedford, TX
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6410 Rockledge Dr #660
Bethesda, Maryland 20817
(301) 571-0019
Center for Cancer & Blood Disorders Widely recognized for its compassionate, expert care, the Center...
1121
mi
from
Bethesda, MD
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684
mi
from
Birmingham, AL
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Canton, Ohio 44710
902
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Canton, OH
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Cary, North Carolina 27511
1060
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Cary, NC
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721
mi
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Chattanooga, TN
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734
mi
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Cincinnati, OH
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340
mi
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Dallas, TX
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347
mi
from
Dallas, TX
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348
mi
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Dallas, TX
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347
mi
from
Dallas, TX
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Dallas, Texas 75251
338
mi
from
Dallas, TX
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Denton, Texas 76210
321
mi
from
Denton, TX
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638
mi
from
El Paso, TX
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Eugene, Oregon 97401
1382
mi
from
Eugene, OR
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8503 Arlington Blvd., Ste. 400
Fairfax, Virginia 22031
(703) 280-5390
Virginia Cancer Specialists, PC Now the world's most advanced cancer treatment capabilities can be found...
1114
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Fairfax, VA
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787
mi
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Flagstaff, AZ
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Fort Meyers, Florida 33916
?
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Fort Meyers, FL
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Fort Worth, Texas 76104
?
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Fort Worth, TX
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Fredericksburg, Texas 78624
519
mi
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Fredericksburg, TX
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572
mi
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Houston, TX
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Huntsville, Alabama 35801
659
mi
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Huntsville, AL
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Indianapolis, Indiana 46227
644
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Indianapolis, IN
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Jacksonville, Florida 32256
1065
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Jacksonville, FL
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1190
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Kingston, PA
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Longview, Texas 75601
402
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Longview, TX
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800
mi
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McAllen, TX
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Midland, Texas 79701
465
mi
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Midland, TX
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3322 West End Avenue
Nashville, Tennessee 37203
(615)329-SCRI (7274)
Sarah Cannon Research Institute Sarah Cannon Research Institute (SCRI) is a global strategic research organization...
618
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Nashville, TN
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New London, Connecticut 06320
1387
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New London, CT
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Orlando, Florida 32804
1139
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Orlando, FL
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Overland Park, Kansas 66210
187
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Overland Park, KS
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Sherman, Texas 75090
292
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Sherman, TX
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St. Louis, Missouri 63141
403
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St. Louis, MO
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1313
mi
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Troy, NY
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Tyler, Texas 75702
398
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Tyler, TX
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Vancover, Washington 98686
1385
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Vancover, WA
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430
mi
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Waco, TX
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26
mi
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Wichita, KS
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