A Study of Nivolumab in Advanced Non-Small Cell Lung Cancer (NSCLC)



Status:Active, not recruiting
Conditions:Lung Cancer, Cancer
Therapuetic Areas:Oncology
Healthy:No
Age Range:18 - Any
Updated:5/4/2018
Start Date:November 13, 2015
End Date:April 15, 2019

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A Master Protocol of Phase 1/2 Studies of Nivolumab in Advanced NSCLC Using Nivolumab as Maintenance After Induction Chemotherapy or as First-line Treatment Alone or in Combination With Standard of Care Therapies (CheckMate 370: CHECKpoint Pathway and nivoluMAb Clinical Trial Evaluation 370)

The purpose of this study is to determine whether nivolumab monotherapy or in combination
with Standard of care (SOC) therapies will provide clinical benefit (i.e., PFS, OS, and DOR)
without unacceptable toxicity in advanced Non-Small Cell Lung Cancer patients.

Epidermal Growth Factor Receptor (EGFR), Anaplastic Lymphoma Kinase (ALK)

**Please note that the study is no longer enrolling patients for Groups A, B, C, and E.

For more information regarding BMS clinical trial participation, please visit
www.BMSStudyConnect.com

Inclusion Criteria:

- Histologically confirmed locally advanced or stage IV NSCLC

- Eastern Cooperative Oncology Group (ECOG) Performance status (PS) 0-2

- Tumor tissue sections must be available for biomarker evaluation

Exclusion Criteria:

- Untreated or active/progressing Central Nervous system (CNS) metastases

- Active, known or suspected autoimmune disease

- Known history of testing positive for HIV or AIDS

- Active or chronic infection of hepatitis B virus or hepatitis C
We found this trial at
134
sites
Flemington, New Jersey 08822
431
mi
from 43215
Flemington, NJ
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3551 Roger Brooke Dr
Fort Sam Houston, Texas 78234
(210) 916-4141
Brooke Army Medical Center Brooke Army Medical Center (BAMC) is the Flagship of Army Medicine!...
1135
mi
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Fort Sam Houston, TX
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Gainesville, Florida 32611
711
mi
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Gainesville, FL
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3700 Johnson Street
Hollywood, Florida 33021
Phone: 954-844-6898
977
mi
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Hollywood, FL
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433 Southwest 10th Street
Ocala, Florida 34471
Phone: 353-732-4032
746
mi
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Ocala, FL
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1871 SE Tiffany Ave # 100
Port Saint Lucie, Florida 34952
889
mi
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Port Saint Lucie, FL
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Abilene, Texas 79606
Phone: 325-692-0188
1070
mi
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Abilene, TX
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Albany, New York 12206
Phone: 518-262-6696
514
mi
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Albany, NY
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3330 Masonic Dr
Alexandria, Louisiana 71301
799
mi
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Alexandria, LA
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1200 S Cedar Crest Blvd
Allentown, Pennsylvania 18103
(610) 402-8000
Lehigh Valley Hospital At Lehigh Valley Health Network, we continually go the extra mile to...
400
mi
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Allentown, PA
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Amarillo, Texas 79106
Phone: 806-358-8654
1081
mi
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Amarillo, TX
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Anderson, Indiana 46011
140
mi
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Anderson, IN
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Annapolis, Maryland 21401
Phone: 443-481-4390
354
mi
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Annapolis, MD
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Arlington, Texas 76012
Phone: 817-664-9600
928
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Arlington, TX
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Athens, Georgia 30607
Phone: 706-353-2990
411
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Athens, GA
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Bakersfield, California 93309
Phone: 661-616-1619
1983
mi
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Bakersfield, CA
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Baltimore, Maryland 20742
(301) 405-1000
Phone: 410-328-8708
University of Maryland As a globally-connected university offering a world-class education, the University of Maryland...
343
mi
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Baltimore, MD
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2401 W Belvedere Ave
Baltimore, Maryland 21215
(410) 601-9000
Sinai Hospital of Baltimore Sinai Hospital of Baltimore provides a broad array of high-quality, cost-effective...
340
mi
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Baltimore, MD
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Beaumont, Texas 77702
Phone: 409-899-7180
926
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Beaumont, TX
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Bedford, Texas 76022
Phone: 817-359-9033
925
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Bedford, TX
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6410 Rockledge Dr #660
Bethesda, Maryland 20817
(301) 571-0019
Phone: 301-571-2016
Center for Cancer & Blood Disorders Widely recognized for its compassionate, expert care, the Center...
320
mi
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Bethesda, MD
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Bethlehem, Pennsylvania 18015
234
mi
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Bethlehem, PA
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Billings, Montana 59102
Phone: 406-238-6290
1344
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Billings, MT
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Birmingham, Alabama 35223
Phone: 205-803-4389
492
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Birmingham, AL
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500 North 8th Street
Bismarck, North Dakota 58501
1005
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Bismarck, ND
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Blacksburg, Virginia 24060
Phone: 540-381-5291
248
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Blacksburg, VA
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Bridgeton, Missouri 63044
404
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Bridgeton, MO
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Charleston, South Carolina 29403
Phone: 843-577-6957
523
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Charleston, SC
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Chattanooga, Tennessee 37404
Phone: 423-698-1844
362
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Chattanooga, TN
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5053 Wooster Rd
Cincinnati, Ohio 45226
(513) 751-2273
Phone: 859-727-2273
Oncology Hematology Care Our more than 60 physicians and advanced practice providers throughout neighborhood offices...
86
mi
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Cincinnati, OH
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2500 Metrohealth Dr
Cleveland, Ohio 44109
(216) 778-7800
MetroHealth Med Ctr The MetroHealth System is one of the largest, most comprehensive health care...
127
mi
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Cleveland, OH
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129
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Cleveland, OH
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Columbia, Maryland 21044
Phone: 410-581-2100
331
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Columbia, MD
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1
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Columbus, OH
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Dallas, Texas 75246
Phone: 214-370-1000
909
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Dallas, TX
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Dallas, Texas 75237
Phone: 214-943-9911
919
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Dallas, TX
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Dallas, Texas 75246
909
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Dallas, TX
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Denton, Texas 76210
910
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Denton, TX
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Easton, Maryland 21601
379
mi
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Easton, MD
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Edina, Minnesota 55435
Phone: 612-884-6300
625
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Edina, MN
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El Paso, Texas 79902
Phone: 915-544-6750
1425
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El Paso, TX
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Erie, Pennsylvania 16505
Phone: 814-838-9000
209
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Erie, PA
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Eugene, Oregon 97401
Phone: 541-683-5001
2055
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Eugene, OR
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1717 13th St
Everett, Washington 98201
(425) 297-5500
Phone: 425-297-5500
Providence Regional Cancer Partnership Founded in 2007, the Providence Regional Cancer Partnership is the result...
2001
mi
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Everett, WA
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8503 Arlington Blvd., Ste. 400
Fairfax, Virginia 22031
(703) 280-5390
Phone: 703-208-3173
Virginia Cancer Specialists, PC Now the world's most advanced cancer treatment capabilities can be found...
316
mi
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Fairfax, VA
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Farmington, New Mexico 87401
1379
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Farmington, NM
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Flower Mound, Texas 75028
Phone: 972-537-4100
912
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Flower Mound, TX
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Fort Myers, Florida 33916
Phone: 239-274-9930
924
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Fort Myers, FL
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Fort Wayne, Indiana 46845
139
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Fort Wayne, IN
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Fort Worth, Texas 76104
Phone: 817-850-2000
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Fort Worth, Texas 76104
Phone: 817-759-7023
937
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Fullerton, California 92835
Phone: 714-446-5804
1960
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Fullerton, CA
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Germantown, Tennessee 38138
Phone: 901-685-5969
501
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Germantown, TN
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Germantown, Tennessee 38138
Phone: 901-683-0055
501
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Germantown, TN
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Glens Falls, New York 12801
536
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Glens Falls, NY
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Grand Junction, Colorado 81501
Phone: 970-298-7500
1357
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Grand Junction, CO
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247
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Grand Rapids, MI
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501 N. Elam Avenue
Greensboro, North Carolina 27403
336-832-1100
Phone: 336-832-0836
Cone Health Cancer Center Located adjacent to Wesley Long Hospital, our Cone Health Cancer Center...
321
mi
from 43215
Greensboro, NC
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501 N. Elam Avenue
Greensboro, North Carolina 27403
336-832-1100
Cone Health Cancer Center Located adjacent to Wesley Long Hospital, our Cone Health Cancer Center...
321
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Greensboro, NC
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Greensboro, North Carolina
321
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Greensboro, NC
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373 North Fayetteville Street
Greensboro, North Carolina 27403
342
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Greensboro, NC
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Greenville, South Carolina 29615
Phone: 864-455-7773
357
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Greenville, SC
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Hattiesburg, Mississippi 39401
Phone: 601-288-8282
692
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Hattiesburg, MS
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Houston, Texas 77024
Phone: 713-467-1722
996
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Houston, TX
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Houston, Texas 77030
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Houston, TX
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Huntington, West Virginia 25701
112
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Huntington, WV
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Irving, Texas 75063
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Irving, TX
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Jackson, Mississippi 39202
Phone: 601-974-5547
661
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Jackson, MS
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Johnson City, New York 13790
Phone: 607-763-6850
396
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Johnson City, NY
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La Jolla, California 92037
1954
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La Jolla, CA
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Lakewood, Colorado 80228
Phone: 303-430-2700
1171
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Lakewood, CO
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9280 W. Sunset Road Suite 100
Las Vegas, Nevada 89148
702.952.1251
Comprehensive Cancer Centers of Nevada Comprehensive Cancer Centers of Nevada (CCCN) is the award-winning multidisciplinary...
1767
mi
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Las Vegas, NV
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Lincoln, Nebraska 68510
Phone: 402-327-7363
719
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Lincoln, NE
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Los Angeles, California 90095
Phone: 310-267-5964
1982
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Los Angeles, CA
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Medford, Oregon 97504
Phone: 541-774-5853
2060
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Medford, OR
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Mesquite, Texas 75150
Phone: 972-686-6411
902
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Mesquite, TX
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Metairie, Louisiana 70006
797
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Metairie, LA
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Miami, Florida 33176
Phone: 305-595-2141
993
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Miami, FL
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Midland, Texas 79701
Phone: 432-688-0843
1196
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Midland, TX
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Mobile, Alabama 36608
Phone: 251-607-5281
703
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Mobile, AL
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Morristown, New Jersey 07960
453
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Morristown, NJ
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Mount Kisco, New York 10549
494
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Mount Kisco, NY
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250 25th Ave N, Ste 100
Nashville, Tennessee 37023
615-320-5090
Tennessee Oncology, PLLC Since 1976 Tennessee Oncology has been providing quality cancer care. In 2013,...
348
mi
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Nashville, TN
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New Braunfels, Texas 78130
Phone: 210-595-5300
1108
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New Braunfels, TX
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481
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New York, NY
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Newnan, Georgia 30265
465
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Newnan, GA
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Niles, Illinois 60714
Phone: 847-827-9060
286
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Niles, IL
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5900 Lake Wright Dr
Norfolk, Virginia 23502
(757) 466-8683
Phone: 757-466-8683
Virginia Oncology Associates Virginia Oncology Associates is an oncology and hematology practice of physicians, specializing...
426
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Norfolk, VA
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Norwich, Connecticut 06360
582
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Norwich, CT
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483
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Nyack, NY
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Omaha, Nebraska 68114
Phone: 402-393-3110
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Omaha, NE
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Paducah, Kentucky 42003
361
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Paducah, KY
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Paris, Texas 75460
Phone: 972-537-4100
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Paris, TX
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Paris, Texas 75460
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Paris, TX
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Phoenix, Arizona 85016
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Phoenix, AZ
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Pinehurst, North Carolina 28374
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Pinehurst, NC
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Plano, Texas 75075
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Plano, TX
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Plano, Texas 75093
Phone: 972-596-7801
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Plano, TX
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Richmond, Virginia 23235
Phone: 804-288-7159
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Richmond, VA
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Saint Petersburg, Florida 33705
Phone: 727-216-1143
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Saint Petersburg, FL
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Salisbury, North Carolina 28144
Phone: 704-638-9000
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