A Study of Nivolumab in Advanced Non-Small Cell Lung Cancer (NSCLC)



Status:Active, not recruiting
Conditions:Lung Cancer, Cancer
Therapuetic Areas:Oncology
Healthy:No
Age Range:18 - Any
Updated:5/4/2018
Start Date:November 13, 2015
End Date:April 15, 2019

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Trial Summary
Trial Overview
Inclusion Criteria

A Master Protocol of Phase 1/2 Studies of Nivolumab in Advanced NSCLC Using Nivolumab as Maintenance After Induction Chemotherapy or as First-line Treatment Alone or in Combination With Standard of Care Therapies (CheckMate 370: CHECKpoint Pathway and nivoluMAb Clinical Trial Evaluation 370)

The purpose of this study is to determine whether nivolumab monotherapy or in combination
with Standard of care (SOC) therapies will provide clinical benefit (i.e., PFS, OS, and DOR)
without unacceptable toxicity in advanced Non-Small Cell Lung Cancer patients.

Epidermal Growth Factor Receptor (EGFR), Anaplastic Lymphoma Kinase (ALK)

**Please note that the study is no longer enrolling patients for Groups A, B, C, and E.

For more information regarding BMS clinical trial participation, please visit
www.BMSStudyConnect.com

Inclusion Criteria:

- Histologically confirmed locally advanced or stage IV NSCLC

- Eastern Cooperative Oncology Group (ECOG) Performance status (PS) 0-2

- Tumor tissue sections must be available for biomarker evaluation

Exclusion Criteria:

- Untreated or active/progressing Central Nervous system (CNS) metastases

- Active, known or suspected autoimmune disease

- Known history of testing positive for HIV or AIDS

- Active or chronic infection of hepatitis B virus or hepatitis C
We found this trial at
134
sites
Maryland Oncology Hematology PA
Columbia, Maryland 21044
Phone: 410-581-2100
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Brooke Army Medical Center
3551 Roger Brooke Dr
Fort Sam Houston, Texas 78234
(210) 916-4141
Brooke Army Medical Center Brooke Army Medical Center (BAMC) is the Flagship of Army Medicine!...
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University of Florida - Shands
Gainesville, Florida 32611
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Memorial Cancer Institute
3700 Johnson Street
Hollywood, Florida 33021
Phone: 954-844-6898
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Ocala Oncology Center
433 Southwest 10th Street
Ocala, Florida 34471
Phone: 353-732-4032
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Ocala, FL
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Hematology Oncology Associates of Treasure Coast
1871 SE Tiffany Ave # 100
Port Saint Lucie, Florida 34952
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Texas Oncology-Abilene
Abilene, Texas 79606
Phone: 325-692-0188
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Abilene, TX
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New York Oncology Hematology PC
Albany, New York 12206
Phone: 518-262-6696
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Albany, NY
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Christus St. Francis Cabrini Cancer Center
3330 Masonic Dr
Alexandria, Louisiana 71301
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Alexandria, LA
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Lehigh Valley Hospital
1200 S Cedar Crest Blvd
Allentown, Pennsylvania 18103
(610) 402-8000
Lehigh Valley Hospital At Lehigh Valley Health Network, we continually go the extra mile to...
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Texas Oncology, P.A. -Amarillo
Amarillo, Texas 79106
Phone: 806-358-8654
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Community Clinical Research Center
Anderson, Indiana 46011
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Anne Arundel Medical Center
Annapolis, Maryland 21401
Phone: 443-481-4390
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Texas Oncology PA - Arlington North
Arlington, Texas 76012
Phone: 817-664-9600
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University Cancer and Blood Center LLC
Athens, Georgia 30607
Phone: 706-353-2990
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Comprehensive Blood and Cancer Center
Bakersfield, California 93309
Phone: 661-616-1619
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University of Maryland
Baltimore, Maryland 20742
(301) 405-1000
Phone: 410-328-8708
University of Maryland As a globally-connected university offering a world-class education, the University of Maryland...
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Sinai Hospital of Baltimore
2401 W Belvedere Ave
Baltimore, Maryland 21215
(410) 601-9000
Sinai Hospital of Baltimore Sinai Hospital of Baltimore provides a broad array of high-quality, cost-effective...
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Texas Oncology-Beaumont
Beaumont, Texas 77702
Phone: 409-899-7180
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Texas Oncology, P.A.
Bedford, Texas 76022
Phone: 817-359-9033
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Center for Cancer & Blood Disorders
6410 Rockledge Dr #660
Bethesda, Maryland 20817
(301) 571-0019
Phone: 301-571-2016
Center for Cancer & Blood Disorders Widely recognized for its compassionate, expert care, the Center...
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St. Luke'S University Hospital Bethlehem
Bethlehem, Pennsylvania 18015
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Saint Vincent Frontier Cancer Center
Billings, Montana 59102
Phone: 406-238-6290
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Alabama Oncology
Birmingham, Alabama 35223
Phone: 205-803-4389
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Cancer Care Center
500 North 8th Street
Bismarck, North Dakota 58501
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Oncology and Hematology Associates of Southwest Virginia Inc.
Blacksburg, Virginia 24060
Phone: 540-381-5291
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St. Louis Cancer Care, LLP
Bridgeton, Missouri 63044
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Charleston Hematology/Oncology Associates, Pa
Charleston, South Carolina 29403
Phone: 843-577-6957
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Chattanooga Oncology Hematology Associates
Chattanooga, Tennessee 37404
Phone: 423-698-1844
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Oncology Hematology Care
5053 Wooster Rd
Cincinnati, Ohio 45226
(513) 751-2273
Phone: 859-727-2273
Oncology Hematology Care Our more than 60 physicians and advanced practice providers throughout neighborhood offices...
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MetroHealth Med Ctr
2500 Metrohealth Dr
Cleveland, Ohio 44109
(216) 778-7800
MetroHealth Med Ctr The MetroHealth System is one of the largest, most comprehensive health care...
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Louis Stokes Cleveland VA Medical Center
Cleveland, Ohio 44106
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Mid Ohio Oncology Hematology, Inc.
Columbus, Ohio
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Texas Oncology, PA
Dallas, Texas 75246
Phone: 214-370-1000
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Texas Oncology/Methodist Charlton Cancer Ctr.
Dallas, Texas 75237
Phone: 214-943-9911
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Texas Oncology, PA
Dallas, Texas 75246
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Texas Oncology, P.A.
Denton, Texas 76210
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Bay Hematology Oncology
Easton, Maryland 21601
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Minnesota Oncology Hematology, PA
Edina, Minnesota 55435
Phone: 612-884-6300
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Texas Oncology
El Paso, Texas 79902
Phone: 915-544-6750
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Erie Regional Cancer Center
Erie, Pennsylvania 16505
Phone: 814-838-9000
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Oncology Associates of Oregon, PC
Eugene, Oregon 97401
Phone: 541-683-5001
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Providence Regional Cancer Partnership
1717 13th St
Everett, Washington 98201
(425) 297-5500
Phone: 425-297-5500
Providence Regional Cancer Partnership Founded in 2007, the Providence Regional Cancer Partnership is the result...
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Virginia Cancer Specialists, PC
8503 Arlington Blvd., Ste. 400
Fairfax, Virginia 22031
(703) 280-5390
Phone: 703-208-3173
Virginia Cancer Specialists, PC Now the world's most advanced cancer treatment capabilities can be found...
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San Juan Oncology Associates
Farmington, New Mexico 87401
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Hunterdon Medical Center
Flemington, New Jersey 08822
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Texas Oncology, P.A.
Flower Mound, Texas 75028
Phone: 972-537-4100
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Florida Cancer Specialists S.
Fort Myers, Florida 33916
Phone: 239-274-9930
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Ft. Wayne Med Onco-Hema Inc
Fort Wayne, Indiana 46845
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Fort Wayne, IN
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Texas Oncology P.A.
Fort Worth, Texas 76104
Phone: 817-850-2000
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The Center for Cancer and Blood Disorders
Fort Worth, Texas 76104
Phone: 817-759-7023
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St. Joseph Heritage Medical Group
Fullerton, California 92835
Phone: 714-446-5804
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Fullerton, CA
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The Jones Clinic, PC
Germantown, Tennessee 38138
Phone: 901-685-5969
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Germantown, TN
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West Cancer Center
Germantown, Tennessee 38138
Phone: 901-683-0055
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Glens Falls Hospital
Glens Falls, New York 12801
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St. Mary's Hospital Regional Cancer Center
Grand Junction, Colorado 81501
Phone: 970-298-7500
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Cancer and Hematology Centers of Western Michigan
Grand Rapids, Michigan 49503
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Cone Health Cancer Center
501 N. Elam Avenue
Greensboro, North Carolina 27403
336-832-1100
Phone: 336-832-0836
Cone Health Cancer Center Located adjacent to Wesley Long Hospital, our Cone Health Cancer Center...
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Cone Health Cancer Center
501 N. Elam Avenue
Greensboro, North Carolina 27403
336-832-1100
Cone Health Cancer Center Located adjacent to Wesley Long Hospital, our Cone Health Cancer Center...
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Moses Cone Health System
Greensboro, North Carolina
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Randolph Cancer Center
373 North Fayetteville Street
Greensboro, North Carolina 27403
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Greenville Health System
Greenville, South Carolina 29615
Phone: 864-455-7773
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Forrest General Cancer Center
Hattiesburg, Mississippi 39401
Phone: 601-288-8282
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Texas Oncology
Houston, Texas 77024
Phone: 713-467-1722
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Houston, TX
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M.D. Anderson Cancer Center
Houston, Texas 77030
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Edwards Comprehensive Cancer Center
Huntington, West Virginia 25701
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Investigational Products Ctr
Irving, Texas 75063
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Jackson Oncology Associates
Jackson, Mississippi 39202
Phone: 601-974-5547
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Broome Oncology, LLC
Johnson City, New York 13790
Phone: 607-763-6850
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Scripps Cancer Center
La Jolla, California 92037
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Rocky Mountain Cancer Centers
Lakewood, Colorado 80228
Phone: 303-430-2700
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Comprehensive Cancer Centers of Nevada
9280 W. Sunset Road Suite 100
Las Vegas, Nevada 89148
702.952.1251
Comprehensive Cancer Centers of Nevada Comprehensive Cancer Centers of Nevada (CCCN) is the award-winning multidisciplinary...
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Southeast Nebraska Cancer Center
Lincoln, Nebraska 68510
Phone: 402-327-7363
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Lincoln, NE
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UCLA Hematology/Oncology Clinic
Los Angeles, California 90095
Phone: 310-267-5964
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Hematology Oncology Associates
Medford, Oregon 97504
Phone: 541-774-5853
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Medford, OR
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Texas Cancer Center of Mesquite
Mesquite, Texas 75150
Phone: 972-686-6411
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East Jefferson General Hospital
Metairie, Louisiana 70006
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Baptist Health Medical Group Oncology, LLC
Miami, Florida 33176
Phone: 305-595-2141
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Miami, FL
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Texas Oncology
Midland, Texas 79701
Phone: 432-688-0843
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Southern Cancer Center
Mobile, Alabama 36608
Phone: 251-607-5281
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Summit Medical Group
Morristown, New Jersey 07960
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Northern Westchester Hospital
Mount Kisco, New York 10549
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Tennessee Oncology, PLLC
250 25th Ave N, Ste 100
Nashville, Tennessee 37023
615-320-5090
Tennessee Oncology, PLLC Since 1976 Tennessee Oncology has been providing quality cancer care. In 2013,...
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Texas Oncology
New Braunfels, Texas 78130
Phone: 210-595-5300
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Columbia University Medical Center (Cumc)
New York, New York 10032
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Cancer Treatment Centers of America
Newnan, Georgia 30265
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Illinois Cancer Specialists
Niles, Illinois 60714
Phone: 847-827-9060
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Virginia Oncology Associates
5900 Lake Wright Dr
Norfolk, Virginia 23502
(757) 466-8683
Phone: 757-466-8683
Virginia Oncology Associates Virginia Oncology Associates is an oncology and hematology practice of physicians, specializing...
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Eastern Ct Hem Onc Assoc
Norwich, Connecticut 06360
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Hematology Oncology Associates of Rockland
Nyack, New York 10960
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Nebraska Cancer Specialists
Omaha, Nebraska 68114
Phone: 402-393-3110
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West Ky Hematology Oncology Group Psc
Paducah, Kentucky 42003
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Texas Oncology
Paris, Texas 75460
Phone: 972-537-4100
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Texas Oncology
Paris, Texas 75460
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Arizona Oncology Assoc, Pc-Hal
Phoenix, Arizona 85016
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First Health of the Carolinas
Pinehurst, North Carolina 28374
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Texas Oncology-Plano East
Plano, Texas 75075
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Texas Oncology Plano West Cancer Center
Plano, Texas 75093
Phone: 972-596-7801
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Virginia Cancer Institute
Richmond, Virginia 23235
Phone: 804-288-7159
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Florida Cancer Specialists
Saint Petersburg, Florida 33705
Phone: 727-216-1143
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Saint Petersburg, FL
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W.G. (Bill) Hefner VA Medical Center
Salisbury, North Carolina 28144
Phone: 704-638-9000
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