Treatment of Obsessive Compulsive Disorder in Children



Status:Archived
Conditions:Psychiatric
Therapuetic Areas:Psychiatry / Psychology
Healthy:No
Age Range:Any
Updated:7/1/2011

Use our guide to learn which trials are right for you!

Treatment of Pediatric OCD for SRI Partial Responders


This study will determine whether cognitive behavioral therapy delivered by either
psychologists or psychiatrists can improve the effectiveness of serotonin reuptake inhibitor
treatment in children with obsessive compulsive disorder.


The vast majority of children with obsessive compulsive disorder (OCD) are given serotonin
reuptake inhibitor (SRI) drugs as initial treatment. However, recommended doses of these
medications leave many children with clinically significant residual symptoms. Health care
experts typically recommend augmenting SRI treatment with cognitive behavioral therapy
(CBT), yet this recommendation is seldom followed. This study will contrast two CBT
augmentation strategies to continued medication management alone: CBT administered by a
psychologist and instructional CBT (I-CBT)administered by a psychiatrist in the context of
ongoing medication management.

All patients in the trial will be eligible to receive a full course of CBT by study end.
Participants in this study will be randomly assigned to receive CBT, I-CBT or continued
medication management. All participants will continue their SRI treatment for 12 weeks.
After the 12-week treatment period, participants who received I-CBT or medication
management alone and who remain symptomatic will be given CBT as will participants who are
asymptomatic but relapse within 6 months after treatment. Assessments will be conducted at
Weeks 0, 4, 8, and 12. Follow-up assessments will be conducted at 3 and 6 months
post-treatment.


We found this trial at
3
sites
593 Eddy Street
Providence, Rhode Island 02903
401-444-4000
Rhode Island Hospital Founded in 1863, Rhode Island Hospital in Providence, RI, is a private,...
?
mi
from
Providence, RI
Click here to add this to my saved trials
3400 Spruce St
Philadelphia, Pennsylvania 19104
 (215) 662-4000
Hospital of the University of Pennsylvania The Hospital of the University of Pennsylvania (HUP) is...
?
mi
from
Philadelphia, PA
Click here to add this to my saved trials
Durham, North Carolina 27705
?
mi
from
Durham, NC
Click here to add this to my saved trials