Cutaneous and Systemic Reactions to Metal Implants



Status:Recruiting
Conditions:Dermatology
Therapuetic Areas:Dermatology / Plastic Surgery
Healthy:No
Age Range:18 - Any
Updated:2/8/2019
Start Date:August 2014
End Date:August 2020
Contact:Marcella Aquino, MD
Email:marcella.aquino@nyulangone.org
Phone:516-663-2097

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Cutaneous and Systemic Reactions to Metal Implants: Utility of Patch Testing Prior and Post Placement of Metal Orthopedic Implants

The purpose of this study is to evaluate if metal patch testing in metal allergic patients is
useful for predicting the development of allergic skin disease or systemic symptoms in
patients who recieve a metal orthopedic implant.

This prospective cohort study will enroll patients with a history of metal allergy who
require implantation of a metal orthopedic device. Patients will be followed for one year
after surgery to determine if any symptoms including rash, itch, joint pain, joint swelling,
and/or joint failure develop post implantation.

Patients will be recruited from two sites: (1) Divisions of Orthopedics and Allergy &
Immunology, Winthrop University Hospital, and (2) Division of Immunology, and Allergy
Section, University of Cincinnati Medical Center.

Inclusion Criteria

1. Age ≥18 years with a history of metal allergy who require joint repair (hip, knee
and/or shoulder)

2. Able to undergo patch testing

Exclusion Criteria

1. Patients on oral immunosuppressant medications within 4 weeks of patch testing or
topical corticosteroids to the back within 1 week of patch testing

2. Patients who are pregnant or breastfeeding
We found this trial at
2
sites
259 1st St
Mineola, New York 11501
(516) 663-0333
Phone: 516-663-2097
Winthrop University Hospital Founded in 1896 by a group of local physicians and concerned citizens,...
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Cincinnati, Ohio 45267
Phone: 513-558-5533
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Cincinnati, OH
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