Body Composition in Infants With Klinefelter Syndrome and Effects of Testosterone Treatment
| Status: | Active, not recruiting |
|---|---|
| Conditions: | Other Indications |
| Therapuetic Areas: | Other |
| Healthy: | No |
| Age Range: | Any |
| Updated: | 1/17/2019 |
| Start Date: | May 8, 2015 |
| End Date: | February 2019 |
This research study in infant males with Klinefelter syndrome (47,XXY) will learn more about
body composition (muscle and fat) and male hormones and look at the effect of testosterone
shots on body composition. The Investigators know that older boys and men with Klinefelter
syndrome often have more fat compared to muscle than adults without Klinefelter syndrome, but
we do not know if this difference is present at birth or develops over time. The
Investigators will learn if body composition and motor skills are improved with testosterone
treatment in infants with Klinefelter syndrome.
body composition (muscle and fat) and male hormones and look at the effect of testosterone
shots on body composition. The Investigators know that older boys and men with Klinefelter
syndrome often have more fat compared to muscle than adults without Klinefelter syndrome, but
we do not know if this difference is present at birth or develops over time. The
Investigators will learn if body composition and motor skills are improved with testosterone
treatment in infants with Klinefelter syndrome.
Inclusion Criteria:
- Male infants with 47,XXY karyotype
Exclusion Criteria:
- Gestational age at birth <36 weeks
- Birth weight <5%ile or >95% for gestational age
- History of thrombosis in a first degree relative
- Exposure to androgen therapy outside of the study protocol.
We found this trial at
1
site
13123 E 16th Ave
Aurora, Colorado 80045
Aurora, Colorado 80045
(720) 777-1234
Principal Investigator: Shanlee M Davis, MD
Phone: 720-777-6073
Children's Hospital Colorado At Children's Hospital Colorado, we see more, treat more and heal more...
Click here to add this to my saved trials
