Study to Enhance Motor Acute Recovery With Intensive Training After Stroke



Status:Completed
Conditions:Neurology
Therapuetic Areas:Neurology
Healthy:No
Age Range:21 - Any
Updated:8/12/2018
Start Date:May 2015
End Date:April 2018

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Stroke often results in limitation of arm movements, from which many people do not fully
recover. We believe that early and intensive therapy is important to enhance recovery of arm
movements after stroke. We are doing this research study to see how much arm movements
improve with intensive therapy in patients have had a stroke in the past 6 weeks.


Inclusion Criteria:

1. Age over 21 years

2. Ischemic stroke confirmed by CT or MRI within the previous 6 weeks

3. No history of prior ischemic or hemorrhagic stroke with associated motor deficits
(prior stroke with no motor symptoms is allowed)

4. Residual unilateral arm weakness with Fugl-Meyer Upper Extremity (FM-UE) score 6-40 at
time of enrollment.

5. Ability to give informed consent and understand the tasks involved.

Exclusion Criteria:

1. Space-occupying hemorrhagic transformation or associated intracranial hemorrhage.

2. Arm impairment that is too severe or too mild on day of baseline testing just prior to
beginning of the study intervention.

3. Recent botox injection to upper limb or planned botox injection over the course of the
7-month study duration.

4. Cognitive impairment, with score on Montreal Cognitive Assessment (MoCA) ≤ 20.

5. History of physical or neurological condition that interferes with study procedures or
assessment of motor function (e.g. severe arthritis, severe neuropathy, Parkinson's
disease).

6. Inability to sit in a chair and perform upper limb exercises for one hour at a time.

7. Participation in another upper extremity rehabilitative therapy study during the study
period.

8. Terminal illness

9. Social and/or personal circumstances that interfere with ability to return for therapy
sessions and follow up assessments.
We found this trial at
3
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116th St and Broadway
New York, New York 10027
(212) 854-1754
Phone: 212-305-0737
Columbia University In 1897, the university moved from Forty-ninth Street and Madison Avenue, where it...
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3400 N Charles St
Baltimore, Maryland 21205
410-516-8000
Phone: 410-614-3460
Johns Hopkins University The Johns Hopkins University opened in 1876, with the inauguration of its...
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107 Zollikerstrasse
Zurich, 8008
Phone: 00412558806
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