A Study of Evacetrapib (LY2484595) in Participants With High Cholesterol



Status:Terminated
Conditions:High Cholesterol
Therapuetic Areas:Cardiology / Vascular Diseases
Healthy:No
Age Range:18 - Any
Updated:4/17/2018
Start Date:October 2014
End Date:December 2015

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The Addition of Evacetrapib to Atorvastatin Compared to Placebo, High Intensity Atorvastatin, and Atorvastatin With Ezetimibe to Evaluate LDL-C Lowering in Patients With Primary Hyperlipidemia - The ACCENTUATE Study

The purpose of the ACCENTUATE study is to evaluate whether the study drug known as
evacetrapib is effective in treating participants with high cholesterol and atherosclerotic
cardiovascular disease (ASCVD) and/or diabetes.


Inclusion Criteria:

- Must be treated with atorvastatin 40 mg/day for at least 30 days prior to screening

- Have an LDL-C >70 mg/deciliter(dL) or non-HDL-C >100 mg/dL

- Have screening triglycerides ≤400 mg/dL (≤4.5 millimoles/Liter)

- Individuals with ASCVD and/or individuals with type 1 or type 2 diabetes

Exclusion Criteria:

- Have a hemoglobin A1c (HbA1c) >9.5%

- New York Heart Association (NYHA) class III or IV congestive heart failure

- History of either a transient ischemic stroke or ischemic stroke <30 days

- History of acute coronary syndrome (ACS) <30 days
We found this trial at
62
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Saint Louis, Missouri 63117
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860 Peachwood Drive
DeLand, Florida 32720
(386) 740-0770
Site Overview Avail Clinical Research is a renowned and experienced clinical research site conducting Phase...
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2128 W Flagler St # 201
Miami, Florida 33144
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Arlington Heights, Illinois 60005
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Asheville, North Carolina 28802
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Baltimore, Maryland 21229
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Baltimore, Maryland 21236
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Bellevue, Washington 98007
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Bossier City, Louisiana 71111
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Boynton Beach, Florida 33437
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Carmichael, California 95608
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Charlotte, North Carolina 28204
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Chicago, Illinois 60607
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Colorado Springs, Colorado 80909
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Columbus, Ohio 43213
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Covington, Georgia 30014
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Crystal Lake, Illinois 60012
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Cumberland, Rhode Island 02864
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Daytona Beach, Florida 32117
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Encino, California 91436
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Fargo, North Dakota 58103
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Fort Lauderdale, Florida 33308
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Gainesville, Georgia 30501
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High Point, North Carolina 27265
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Honolulu, Hawaii 96814
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Huntsville, Alabama 35801
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Hutchinson, Kansas 67502
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Hyannis, Massachusetts 02601
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Indianapolis, Indiana 46237
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Indianapolis, Indiana 46260
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Inverness, Florida 34452
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Irvine, California 92618
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Kenosha, Wisconsin 53142
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Kingsport, Tennessee 37660
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Las Vegas, Nevada 89102
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Long Beach, California 90822
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Louisville, Kentucky 40207
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Meridian, Idaho 83646
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Mesa, Arizona 85201
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Methuen, Massachusetts 01844
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Mount Pleasant, South Carolina 29464
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New York, New York 10004
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Oklahoma City, Oklahoma 73135
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Phoenix, Arizona 85020
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Port Orange, Florida 32127
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Portland, Oregon 97225
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Rancho Cucamonga, California 91730
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Rapid City, South Dakota 57701
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Richmond, VA
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Rocky Mount, North Carolina 27804
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Saratoga Springs, New York 12866
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Spokane, Washington 99204
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Spring Valley, California 91978
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Tomball, Texas 77375
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Tustin, California 92780
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Walnut creek, California 94598
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Williamsville, New York 14221
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1907 Tradd Ct
Wilmington, North Carolina 28401
(910) 799-5500
PMG Research of Wilmington PMG Research of Wilmington has two offices situated in a 1...
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