Circadian Rhythms and Cardiovascular Risk
| Status: | Recruiting |
|---|---|
| Conditions: | Insomnia Sleep Studies, Pulmonary |
| Therapuetic Areas: | Psychiatry / Psychology, Pulmonary / Respiratory Diseases |
| Healthy: | No |
| Age Range: | 40 - 80 |
| Updated: | 2/8/2019 |
| Start Date: | August 2014 |
| End Date: | December 2019 |
| Contact: | Saurabh Thosar, PhD |
| Email: | circadian@ohsu.edu |
| Phone: | 503-346-3808 |
The purpose of this study is to understand how behaviors and the effects of the body's
internal clock (called the circadian pacemaker) affect the control of the heart and blood
pressure.
People with Obstructive Sleep Apnea (OSA) are hypothesized to have altered circadian
amplitudes in certain key indices of cardiovascular (CV) and an abnormally advanced circadian
phase in some of the same key indices of CV risk. The investigators hypothesize that such
changes, taken together, may explain the different timing of heart attack and sudden cardiac
death in OSA.
internal clock (called the circadian pacemaker) affect the control of the heart and blood
pressure.
People with Obstructive Sleep Apnea (OSA) are hypothesized to have altered circadian
amplitudes in certain key indices of cardiovascular (CV) and an abnormally advanced circadian
phase in some of the same key indices of CV risk. The investigators hypothesize that such
changes, taken together, may explain the different timing of heart attack and sudden cardiac
death in OSA.
- BMI less than 40
- Moderate to severe OSA (AHI)>15
- No current or previous pharmacological treatment for hypertension
We found this trial at
1
site
3181 Southwest Sam Jackson Park Road
Portland, Oregon 97239
Portland, Oregon 97239
503 494-8311
Principal Investigator: Steven A Shea, PhD
Phone: 503-346-3808
Oregon Health and Science University In 1887, the inaugural class of the University of Oregon...
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