Long-Term Effectiveness And Safety Of CP-690,550 For The Treatment Of Rheumatoid Arthritis



Status:Completed
Conditions:Arthritis, Rheumatoid Arthritis
Therapuetic Areas:Rheumatology
Healthy:No
Age Range:18 - Any
Updated:11/1/2018
Start Date:February 5, 2007
End Date:October 26, 2017

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A Long-term, Open-label Follow-up Study Of Tofacitinib (Cp-690,550) For Treatment Of Rheumatoid Arthritis

The purpose of this study is to determine the long-term effectiveness and safety of
CP-690,550 for the treatment of rheumatoid arthritis. Subjects are eligible for this study
only after participating in another "qualifying" study of CP-690,550

A sub-study will be conducted within the A3921024 study, this study will evaluate the immune
response to pneumococcal and influenza vaccines in patients receiving CP-690,550


Inclusion Criteria:

- Subjects who have participated in a randomized "qualifying" study of CP-690,550 for
the treatment of rheumatoid arthritis

Vaccine sub-study visit

- Subjects actively participating in Study A3921024 must have completed at least 3
months of continuous 10 mg BID CP-690,550 treatment in A3921024 as defined by >80%
compliance with prescribed dose consumption of CP-690,550 over the previous 3 months.

Exclusion Criteria:

- Serious medical conditions that would make treatment with CP-690,550 potentially
unsafe

Vaccine sub-study visit

1. Any documented influenza or pneumococcal infection within the last 3 months prior to
randomization in this study

2. Received any vaccine within 1 month prior to randomization in this study

3. Received an influenza vaccine within 6 months or a pneumococcal vaccine within 5 years
of randomization in this study.
We found this trial at
149
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1720 2nd Ave S
Birmingham, Alabama 35233
(205) 934-4011 
University of Alabama at Birmingham The University of Alabama at Birmingham (UAB) traces its roots...
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4085 University Blvd S # 1
Jacksonville, Florida 32216
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1521 Gull Road Kalamazoo
Kalamazoo, Michigan 49048
269-226-4803
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Los Angeles, California 90095
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University of California at Los Angeles The University of California, Los Angeles (UCLA) is an...
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1211 Medical Center Dr
Nashville, Tennessee 37232
(615) 322-5000
Vanderbilt Univ Med Ctr Vanderbilt University Medical Center (VUMC) is a comprehensive healthcare facility dedicated...
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6141 Sunset Dr # 301
South Miami, Florida 33143
(305) 598-3125
Miami Research Associates Miami Research Associates (MRA) is the largest privately-owned multi-specialty clinical research center...
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South Miami, FL
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Albany, New York 12206
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Allen, TX
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Atlanta, Georgia 30342
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Austin, Texas 78705
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Baton Rouge, Louisiana 70809
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Battle Creek, Michigan 49015
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Bingham Farms, Michigan 48025
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Boulder, Colorado 80304
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725 Uruguay
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Clarksburg, West Virginia 26301
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Columbia, Missouri 65203
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104 Jesse Hall
Columbia, Missouri 65211
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University Of Missouri-Columbia The University of Missouri was founded in 1839 in Columbia, Mo., as...
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Cumberland, Maryland 21502
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3310 Live Oak St
Dallas, Texas 75204
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Baylor Research Institute Baylor Research Institute (BRI) is a dedicated research center for finding prevention...
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Fair Oaks, California 95628
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263 Farmington Ave
Farmington, Connecticut 06030
(860) 679-2000
University of Connecticut Health Center UConn Health is a vibrant, integrated academic medical center that...
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Frederick, Maryland 21702
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Gilbert, Arizona 85234
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Greenville, South Carolina 29601
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Hamden, Connecticut 06518
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Hickory, North Carolina 28602
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Indianapolis, Indiana 46227
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1 Medical Center Dr
Lebanon, New Hampshire 03756
 (603) 650-5000
Dartmouth Hitchcock Medical Center Dartmouth-Hitchcock is a national leader in patient-centered health care and building...
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Lexington, Kentucky 40504
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25 Oak Avenue
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Mayfield, Ohio 44143
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2160 South 1st Avenue
Maywood, Illinois 60153
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3555 NW 58th St # 800
Oklahoma City, Oklahoma 73112
(405) 447-8839
Lynn Health Science Institute Our mission is to provide clinical trials research and health services...
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Onalaska, Wisconsin 54650
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