Study of Nivolumab in Patients With Classical Hodgkin's Lymphoma (Registrational)
Status: | Active, not recruiting |
---|---|
Conditions: | Lymphoma |
Therapuetic Areas: | Oncology |
Healthy: | No |
Age Range: | 18 - Any |
Updated: | 12/13/2018 |
Start Date: | July 19, 2014 |
End Date: | October 1, 2020 |
Non-Comparative, Multi-Cohort, Single Arm, Open-Label, Phase 2 Study of Nivolumab (BMS-936558) in Classical Hodgkin Lymphoma (cHL) Subjects
The purpose of this study is to evaluate the efficacy and safety of Nivolumab in previously
treated (cohorts, A, B & C) or newly diagnosed (cohort D) classical Hodgkin Lymphoma
subjects.
treated (cohorts, A, B & C) or newly diagnosed (cohort D) classical Hodgkin Lymphoma
subjects.
For more information regarding BMS clinical trial participation, please visit
www.BMSStudyConnect.com
Inclusion Criteria:
- Eastern Cooperative Oncology Group (ECOG) performance status 0 or 1
- Must have received prior high-dose conditioning chemotherapy followed by autologous
stem cell transplant (ASCT) as a part of salvage therapy for cHL (cohort A, B & C -
enrolment closed)
- Subjects may be Brentuximab vedotin- naïve, or may have had prior Brentuximab vedotin
treatment (cohort A, B & C - enrolment closed)
- Newly diagnosed and previously untreated classical Hodgkin Lymphoma (cohort D)
Exclusion Criteria:
- Known central nervous system lymphoma
- Subjects with nodular lymphocyte-predominant Hodgkin Lymphoma
- Prior allogeneic stem cell transplantation (SCT)
- Chest radiation ≤ 24 weeks prior to first dose
- Carmustine ≥ 600 mg/m² received as part of the pre-transplant conditioning regimen
We found this trial at
15
sites
1275 York Ave
New York, New York 10021
New York, New York 10021
(212) 639-2000
Phone: 212-639-6104
Memorial Sloan Kettering Cancer Center Memorial Sloan Kettering Cancer Center — the world's oldest and...
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330 Brookline Ave
Boston, Massachusetts 02215
Boston, Massachusetts 02215
617-667-7000
Phone: 617-667-9920
Beth Israel Deaconess Medical Center Beth Israel Deaconess Medical Center (BIDMC) is one of the...
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4100 John R
Detroit, Michigan 48201
Detroit, Michigan 48201
800-527-6266
Phone: 313-576-8787
Barbara Ann Karmanos Cancer Institute Karmanos is based in southeast Michigan, in midtown Detroit, and...
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8700 Beverly Blvd # 8211
Los Angeles, California 90048
Los Angeles, California 90048
(1-800-233-2771)
Phone: 310-248-8542
Cedars Sinai Med Ctr Cedars-Sinai is known for providing the highest quality patient care. Our...
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1211 Medical Center Dr
Nashville, Tennessee 37232
Nashville, Tennessee 37232
(615) 322-5000
Phone: 615-343-4091
Vanderbilt Univ Med Ctr Vanderbilt University Medical Center (VUMC) is a comprehensive healthcare facility dedicated...
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450 Brookline Ave
Boston, Massachusetts 2215
Boston, Massachusetts 2215
617-632-3000
Phone: 617-632-2305
Dana-Farber Cancer Institute Since it’s founding in 1947, Dana-Farber has been committed to providing adults...
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