Study of Nivolumab in Patients With Classical Hodgkin's Lymphoma (Registrational)



Status:Active, not recruiting
Conditions:Lymphoma
Therapuetic Areas:Oncology
Healthy:No
Age Range:18 - Any
Updated:12/13/2018
Start Date:July 19, 2014
End Date:October 1, 2020

Use our guide to learn which trials are right for you!

Non-Comparative, Multi-Cohort, Single Arm, Open-Label, Phase 2 Study of Nivolumab (BMS-936558) in Classical Hodgkin Lymphoma (cHL) Subjects

The purpose of this study is to evaluate the efficacy and safety of Nivolumab in previously
treated (cohorts, A, B & C) or newly diagnosed (cohort D) classical Hodgkin Lymphoma
subjects.


For more information regarding BMS clinical trial participation, please visit
www.BMSStudyConnect.com

Inclusion Criteria:

- Eastern Cooperative Oncology Group (ECOG) performance status 0 or 1

- Must have received prior high-dose conditioning chemotherapy followed by autologous
stem cell transplant (ASCT) as a part of salvage therapy for cHL (cohort A, B & C -
enrolment closed)

- Subjects may be Brentuximab vedotin- naïve, or may have had prior Brentuximab vedotin
treatment (cohort A, B & C - enrolment closed)

- Newly diagnosed and previously untreated classical Hodgkin Lymphoma (cohort D)

Exclusion Criteria:

- Known central nervous system lymphoma

- Subjects with nodular lymphocyte-predominant Hodgkin Lymphoma

- Prior allogeneic stem cell transplantation (SCT)

- Chest radiation ≤ 24 weeks prior to first dose

- Carmustine ≥ 600 mg/m² received as part of the pre-transplant conditioning regimen
We found this trial at
15
sites
1275 York Ave
New York, New York 10021
(212) 639-2000
Phone: 212-639-6104
Memorial Sloan Kettering Cancer Center Memorial Sloan Kettering Cancer Center — the world's oldest and...
?
mi
from
New York, NY
Click here to add this to my saved trials
330 Brookline Ave
Boston, Massachusetts 02215
617-667-7000
Phone: 617-667-9920
Beth Israel Deaconess Medical Center Beth Israel Deaconess Medical Center (BIDMC) is one of the...
?
mi
from
Boston, MA
Click here to add this to my saved trials
185 Cambridge Street
Boston, Massachusetts 02114
617-724-5200
?
mi
from
Boston, MA
Click here to add this to my saved trials
4100 John R
Detroit, Michigan 48201
800-527-6266
Phone: 313-576-8787
Barbara Ann Karmanos Cancer Institute Karmanos is based in southeast Michigan, in midtown Detroit, and...
?
mi
from
Detroit, MI
Click here to add this to my saved trials
8700 Beverly Blvd # 8211
Los Angeles, California 90048
(1-800-233-2771)
Phone: 310-248-8542
Cedars Sinai Med Ctr Cedars-Sinai is known for providing the highest quality patient care. Our...
?
mi
from
Los Angeles, CA
Click here to add this to my saved trials
1211 Medical Center Dr
Nashville, Tennessee 37232
(615) 322-5000
Phone: 615-343-4091
Vanderbilt Univ Med Ctr Vanderbilt University Medical Center (VUMC) is a comprehensive healthcare facility dedicated...
?
mi
from
Nashville, TN
Click here to add this to my saved trials
Allentown, Pennsylvania 18105
Phone: 610-402-7880
?
mi
from
Allentown, PA
Click here to add this to my saved trials
Atlanta, Georgia 30322
?
mi
from
Atlanta, GA
Click here to add this to my saved trials
450 Brookline Ave
Boston, Massachusetts 2215
617-632-3000
Phone: 617-632-2305
Dana-Farber Cancer Institute Since it’s founding in 1947, Dana-Farber has been committed to providing adults...
?
mi
from
Boston, MA
Click here to add this to my saved trials
?
mi
from
Hackensack, NJ
Click here to add this to my saved trials
Houston, Texas 77030
?
mi
from
Houston, TX
Click here to add this to my saved trials
?
mi
from
Innsbruck,
Click here to add this to my saved trials
?
mi
from
Los Angeles, CA
Click here to add this to my saved trials
New York, New York 10021
Phone: 212-746-2062
?
mi
from
New York, NY
Click here to add this to my saved trials
Rochester, Minnesota 55905
Phone: 507-538-1397
?
mi
from
Rochester, MN
Click here to add this to my saved trials