A Study of Galcanezumab (LY2951742) in Participants With Migraine Headache



Status:Completed
Conditions:Migraine Headaches, Migraine Headaches
Therapuetic Areas:Neurology
Healthy:No
Age Range:18 - 65
Updated:11/24/2018
Start Date:July 7, 2014
End Date:February 12, 2018

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A Phase 2b, Randomized, Double-Blind, Placebo-Controlled Study of Galcanezumab in Patients With Episodic Migraine

The main purpose of this study is to evaluate whether the study drug known as galcanezumab is
safe and effective in the prevention of migraine headaches.


Inclusion Criteria:

- Participants with a history of migraine of at least 1 year prior to enrollment.

- Migraine onset prior to age 50.

Exclusion Criteria:

- Current enrollment in, or discontinuation within the last 30 days from, a clinical
trial involving any investigational drug or device.

- Current use or any prior exposure to any CGRP antibody, any antibody to the CGRP
receptor, or antibody to nerve growth factor (NGF).

- History of migraine subtypes including hemiplegic migraine, ophthalmoplegic migraine,
and basilar-type migraine.

- Have a history or presence of other medical illness that indicates a medical problem
that would preclude study participation.

- Failure to respond to more than two adequately dosed effective migraine prevention
treatments.

- Evidence of significant active psychiatric disease, in the opinion of the
investigator.

- Women who are pregnant or nursing.
We found this trial at
40
sites
860 Peachwood Drive
DeLand, Florida 32720
(386) 740-0770
Site Overview Avail Clinical Research is a renowned and experienced clinical research site conducting Phase...
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1000 Alpine
Boulder, Colorado 80304
303-443-7229
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104 SE 1st Avenue
Ocala, Florida 34471
352-629-5800
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Albuquerque, New Mexico
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Austin, Texas 78759
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Austin, Texas 78731
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Baltimore, Maryland 21208
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Bellevue, Washington 98007
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Boston, Massachusetts 02135
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Edgewood, Kentucky 41017
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Gilbert, Arizona 85234
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Greensboro, North Carolina 27408
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Kalamazoo, Michigan 49009
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Long Beach, California 90806
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Los Alamitos, California 90720
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Maitland, Florida 32751
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Memphis, Tennessee 38119
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Mount Pleasant, South Carolina 29464
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Newport Beach, California 92660
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1020 Walnut St
Philadelphia, Pennsylvania 19107
(215) 955-6000
Thomas Jefferson University We are dedicated to the health sciences and committed to educating professionals,...
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Phoenix, Arizona 85023
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Phoenix, Arizona 85004
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Plainview, New York 11803
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Portland, Oregon 97210
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Rancho Mirage, California 92270
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Rochester, New York 14609
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Saint Louis, Missouri 63141
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San Diego, California 92108
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San Diego, California 92123
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Santa Monica, California 90404
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Seattle, Washington 98105
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Springfield, Missouri 65807
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Stamford, Connecticut 06905
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1901 S Hawthorne Rd #306
Winston-Salem, North Carolina 27103
(336) 768-8062
PMG Research of Winston-Salem PMG Research of Winston-Salem, founded in 1979, occupies a 10,000 square...
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