Novel Measure of Social Deficits in Children

Conditions:Neurology, Psychiatric, Psychiatric, ADHD, Autism
Therapuetic Areas:Neurology, Psychiatry / Psychology, Other
Age Range:6 - 11
Start Date:February 2014
End Date:June 2016
Contact:Garet P Lahvis, PhD
Phone:503 346 0820

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Oregon Animation Test for Social Reciprocity (OATS)

Autism Spectrum Disorders (ASD) feature impairments in social interaction and communication.
Drug and behavioral treatments for ASD are undergoing rapid development, yet our diagnostic
tools are not suitable for efficacy assessment. The Autism-Diagnosis Observational Schedule
(ADOS) is a clinical interview with the child and the gold standard for diagnosis. However,
this test is subjective, course grained and costly, precluding repeated tests of the same
child to assess treatment efficacy and large-scale control assessments of typically
developing (TD) children. For these reasons, the ADOS can impede imaging and genetic

In light of these concerns, the Oregon Animation Test for Social Reciprocity (OATS) will be
developed to evaluate distinct autistic behavioral phenotypes, including joint attention,
empathy, imitation, and lack of narrative coherence. The main idea of OATS is that animated
characters and social scenarios are presented on a computer screen while the responses of
the child are recorded by video camera, microphone, and eye-tracking equipment. Animations
are used to test each behavioral phenotype of autism. The long-term vision for OATS is to
evaluate behavioral and physiological responses of autistic children, including heart rate
variability, pupil dilation, and EEG. Our first objective is to use existing animations to
build an OATS "Prototype" that discriminates autistic from normal children (Aim 1). From
these results, and use of a defined library of still frame posed images, we will design our
own animation platform to assess differences between autistic and normal children (Aim 2).

Please see the brief summary above.

Inclusion Criteria:

- 6-11 years of age with autism,

- ADHD, or typical

Exclusion Criteria:

- IQ below 70.
We found this trial at
Portland, Oregon 97201
Portland, OR
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3181 Southwest Sam Jackson Park Road
Portland, Oregon 97239
503 494-8311
Oregon Health and Science University In 1887, the inaugural class of the University of Oregon...
Portland, OR
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