An Extension Study in Participants With Moderate to Severe Rheumatoid Arthritis



Status:Active, not recruiting
Conditions:Arthritis, Rheumatoid Arthritis
Therapuetic Areas:Rheumatology
Healthy:No
Age Range:18 - Any
Updated:12/6/2018
Start Date:June 27, 2013
End Date:March 22, 2024

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A Phase 3, Multicenter Study to Evaluate the Long-Term Safety and Efficacy of Baricitinib in Patients With Rheumatoid Arthritis

The purpose of this study is to investigate the long-term safety and any side effects of
baricitinib in participants who have completed a previous baricitinib rheumatoid arthritis
study.

The study provides for 7 years of additional treatment with baricitinib.


Inclusion Criteria:

- Have completed the final active treatment in study JADV (NCT01710358), JADZ
(NCT01711359), JADX (NCT01721057), JADW (NCT01721044), JADA (NCT01185353) or JAGS
(planned start date in August 2014)

Exclusion Criteria:

- Have significant uncontrolled cerebro-cardiovascular (eg, myocardial infarction [MI],
unstable angina, unstable arterial hypertension, severe heart failure, or
cerebrovascular accident), respiratory, hepatic, renal, gastrointestinal, endocrine,
hematologic, neuropsychiatric disorders, or abnormal laboratory values that developed
during a previous baricitinib study that, in the opinion of the investigator, pose an
unacceptable risk to the participant if investigational product continues to be
administered

- Have a known hypersensitivity to baricitinib or any component of this investigational
product

- Had investigational product permanently discontinued at any time during a previous
baricitinib study

- Had temporary investigational product interruption at the final study visit of a
previous baricitinib study and, in the opinion of the investigator, this poses an
unacceptable risk for participation in the study

- Have any other condition that, in the opinion of the investigator, renders the
participant unable to understand the nature, scope, and possible consequences of the
study or precludes the participant from following and completing the protocol
We found this trial at
68
sites
Grand Rapids, Michigan 49546
1847
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Grand Rapids, MI
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1044 SW 44th Street
Oklahoma City, Oklahoma 73109
405-616-4888
1164
mi
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Oklahoma City, OK
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3181 Southwest Sam Jackson Park Road
Portland, Oregon 97239
503 494-8311
Oregon Health and Science University In 1887, the inaugural class of the University of Oregon...
827
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Portland, OR
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Albany, New York 12206
2439
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Albany, NY
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Albuquerque, New Mexico
649
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Albuquerque, NM
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2002
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Asheville, NC
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Bahía Blanca,
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Bethlehem, Pennsylvania 18017
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Bethlehem, PA
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Boise, Idaho 83702
666
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Boise, ID
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Boulder, Colorado 80304
812
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Boulder, CO
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Boynton Beach, Florida 33472
2309
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Boynton Beach, FL
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2103
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Charlotte, NC
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Chesapeake, Virginia 23320
2340
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Chesapeake, VA
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Columbia, Missouri 65211
(573) 882-2121
University of Missouri T he University of Missouri was founded in 1839 in Columbia, Mo.,...
1460
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Columbia, MO
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Cumberland, Maryland 21502
2185
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Cumberland, MD
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Cypress, Texas 77429
1308
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Cypress, TX
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1225
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Dallas, TX
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Danbury, Connecticut 06810
2458
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Danbury, CT
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Denver, Colorado 80230
822
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Denver, CO
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Duncansville, Pennsylvania 16635
2201
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Duncansville, PA
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1611
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Flowood, MS
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Franklin, Wisconsin 53132
1720
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Franklin, WI
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Freehold, New Jersey 07728
2419
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Freehold, NJ
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Fresno, California 93720
216
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Fresno, CA
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336
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Glendale, AZ
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Hartsdale, New York 10530
2442
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Hartsdale, NY
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Indianapolis, Indiana 46202
1793
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Indianapolis, IN
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Indianapolis, Indiana 46227
1793
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Indianapolis, IN
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Indianapolis, Indiana 46260
1792
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Indianapolis, IN
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Kalamazoo, Michigan 49009
1833
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Kalamazoo, MI
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Kennewick, Washington 99336
840
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Kennewick, WA
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La Jolla, California 92037
95
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La Jolla, CA
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Lansing, Michigan 48910
1895
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Lansing, MI
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Lansing, Michigan 48910
1893
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Lansing, MI
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Las Vegas, Nevada 89128
217
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Las Vegas, NV
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Lewes, Delaware 19958
2383
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Lewes, DE
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923
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Lubbock, TX
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355
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Mesa, AZ
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Middleburg Heights, Ohio 44130
2025
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Middleburg Heights, OH
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Myrtle Beach, South Carolina 29572
2230
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Naples, Florida 34102
2220
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Nassau Bay, Texas 77058
1378
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Nassau Bay, TX
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New Port Richey, Florida 34652
2114
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New Port Richey, FL
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Orlando, Florida 32804
2182
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Orlando, FL
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2185
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Orlando, FL
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Palm Desert, California 92260
96
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Palm Desert, CA
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Palm Harbor, Florida 34684
2117
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Palm Harbor, FL
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Palo Alto, California 94305
328
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Peoria, Arizona 85381
333
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Peoria, AZ
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Philadelphia, Pennsylvania 19152
2375
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Phoenix, Arizona 85023
343
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2248
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Rochester, NY
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Saint Louis, Missouri 63117
1566
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Saint Louis, Missouri 63141
1558
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Santa Maria, California 93454
32
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Santa Maria, CA
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Seattle, Washington 98133
970
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Seattle, WA
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2306
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Tamarac, FL
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Tampa, Florida 33613
2132
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Tampa, Florida 33614
2132
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Toms River, New Jersey 08755
2426
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Trumbull, Connecticut 06611
2471
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Trumbull, CT
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Tucson, Arizona 85721
(520) 621-2211
University of Arizona The University of Arizona is a premier, public research university. Established in...
427
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Tulsa, Oklahoma 74135
1253
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Upland, California 91786
20
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Vancouver, Washington 98664
833
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Vancouver, WA
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Vernon Hills, Illinois 60061
1716
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Vernon Hills, IL
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Webster, Texas 77508
1372
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Webster, TX
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Wyomissing, Pennsylvania 19610
2331
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Wyomissing, PA
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