Vision Testing in Patients With Partial Seizures Receiving Either Lyrica or Placebo



Status:Recruiting
Conditions:Neurology
Therapuetic Areas:Neurology
Healthy:No
Age Range:18 - 65
Updated:3/17/2019
Start Date:July 26, 2006
End Date:November 11, 2019
Contact:Pfizer CT.gov Call Center
Email:ClinicalTrials.gov_Inquiries@pfizer.com
Phone:1-800-718-1021

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PROSPECTIVE RANDOMIZED 12-WEEK CONTROLLED STUDY OF VISUAL FIELD CHANGE IN SUBJECTS WITH PARTIAL SEIZURES RECEIVING PREGABALIN OR PLACEBO

Patients with partial seizures currently taking 1-3 antiepileptic medications will have a
50:50 chance to receive Lyrica 300 mg per day or placebo (no active ingredients) added on to
their current medications for 3 months. Neither the study doctor nor the patient will know
the medication assignment. Vision testing will be performed prior to receiving the study
treatment and at the end of the study to see if there are any changes.


Inclusion Criteria:

- Epilepsy partial seizure subjects.

- Currently taking 1 to 3 antiepileptic drugs.

Exclusion Criteria:

- Pre-existing eye diseases (glaucoma).

- Insufficient response to pregabalin in the treatment of partial seizure, or patients
currently receiving pregabalin treatment.
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Fulton, Maryland 20759
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