The Epidemiology, Process and Outcomes of Spine Oncology (EPOSO)

Status:	Active, not recruiting
Healthy:	No
Age Range:	18 - 75
Updated:	6/23/2018
Start Date:	August 2013
End Date:	December 2020

The Epidemiology, Process and Outcomes of Spine Oncology

The main purpose of this study is to utilize a comprehensive, prospective clinical database
to collect patient, diagnostic and treatment variables along with disease specific and
generic health related quality of life (HRQOL) data on consecutively treated patients with
metastatic spine tumors. The objectives are to determine the validity and reliability of the
Spine Cancer Outcomes Questionnaire (SCOQ) for use in the assessment of spine tumor outcomes,
to determine if the Spine Instability Neoplastic Score (SINS) Classification is a valid tool
for predicting the stability of spine in metastatic spine disease, and to determine the
efficacy of surgery versus radiotherapy for the treatment of impending instability secondary
to metastatic disease of the spine.

Inclusion Criteria:

- Signed informed consent

- Age between 18 and 75 years

- Able to read and write English at an elementary level

- Diagnosis of metastatic tumor of the spine

Exclusion Criteria:

- The primary cancer site is central nervous system or spine

- History of substance abuse (recreational drugs, alcohol) within 12 months prior to
screening

- Is a prisoner

- A disease or condition that would, in opinion of the investigator, preclude accurate
evaluation (e.g. significant psychiatric disease)

We found this trial at

sites

Hospital of the University of Pennsylvania

3400 Spruce St
Philadelphia, Pennsylvania 19104

(215) 662-4000