Study to Evaluate the Effects of BMS-813160 on Protein Loss in the Urine of Subjects With Type 2 Diabetes and Diabetic Kidney Disease
| Status: | Completed |
|---|---|
| Conditions: | Renal Impairment / Chronic Kidney Disease, Diabetes |
| Therapuetic Areas: | Endocrinology, Nephrology / Urology |
| Healthy: | No |
| Age Range: | 18 - 85 |
| Updated: | 4/21/2016 |
| Start Date: | March 2013 |
| End Date: | June 2015 |
A Double-Blind, Placebo-Controlled, Randomized, Two-stage, Parallel-Group, Adaptive Design Phase 2a Study to Evaluate the Effects of BMS-813160 in Subjects With Type 2 Diabetes Mellitus and Diabetic Kidney Disease (DKD) Who Have Residual Macroalbuminuria Despite Treatment With an Inhibitor of the Renin-Angiotensin System
The purpose of this study is to determine whether BMS-813160 will reduce the amount of
protein loss in the urine of subjects with type 2 diabetes and diabetic kidney disease
protein loss in the urine of subjects with type 2 diabetes and diabetic kidney disease
For more information regarding BMS clinical trial participation, please visit
www.BMSStudyConnect.com
Inclusion Criteria:
- Clinical diagnosis of type 2 diabetes mellitus with macroalbuminuria (UACR between
200 and 3500 mg/g)
- Background angiotensin converting enzyme inhibitor (ACEI) or angiotensin-receptor
blocker (ARB) therapy
Exclusion Criteria:
- Clinical diagnosis of type 1 diabetes
- Unstable cardiovascular, metabolic, or other chronic disease status
- Estimated glomerular filtration rate (eGFR) <30 mL/min/1.73 m2
- High risk of infection or immune compromise
- Clinically significant ECG conduction abnormalities
- Drugs with significant potential to affect BMS-813160 exposure
We found this trial at
38
sites
Thomas Jefferson University We are dedicated to the health sciences and committed to educating professionals,...
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Emory University School of Medicine Emory University School of Medicine has 2,359 full- and part-time...
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Duke University Younger than most other prestigious U.S. research universities, Duke University consistently ranks among...
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1211 Medical Center Dr
Nashville, Tennessee 37232
Nashville, Tennessee 37232
(615) 322-5000
Vanderbilt Univ Med Ctr Vanderbilt University Medical Center (VUMC) is a comprehensive healthcare facility dedicated...
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1969 W Ogden Ave
Chicago, Illinois 60612
Chicago, Illinois 60612
(312) 864-6000
John H. Stroger, Jr. Hospital of Cook County The Level 1 Trauma Center is one...
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The Ohio State University, Wexner Medical Center Located in Columbus, The Ohio State University Wexner...
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UCLA UCLA's primary purpose as a public research university is the creation, dissemination, preservation and...
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