Betrnet Stem Cells and the Origins of Barrett's Esophagus Project 3 RF Ablation



Status:Active, not recruiting
Conditions:Gastrointestinal
Therapuetic Areas:Gastroenterology
Healthy:No
Age Range:18 - Any
Updated:1/20/2019
Start Date:January 2012
End Date:August 2020

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Stem Cells And The Origins Of Barrett's Esophagus:Identification Of Novel Biomarkers And Gene Signatures In Barrett's Esophagus

The purpose of this study is to determine biomarkers which can predict response to ablation
therapy in patients with Barretts esophagus.

This Project is designed to identify biologically-based and clinically-useful biomarkers of
tissue at risk for neoplastic progression as well as of response to ablation therapy. These
results will result in improved risk stratification in BE and better targeting of resources
for patients who are candidates for ablative therapy, while simultaneously providing key
information regarding the origins of Barrett's esophagus.

Inclusion Criteria:

- Barrett's esophagus with high grade dysplasia or intramucosal (early) adenocarcinoma.

- BE length ≥ 2 cm and ≤ 8 cm.

- Able to return every 3 months for one year after ablation

Exclusion Criteria:

- Patients who are unable to be compliant with follow-up endoscopies

- patients who cannot tolerate Proton Pump inhibitors

- pre-existing esophageal strictures

- pregnant or nursing women
We found this trial at
2
sites
116th St and Broadway
New York, New York 10027
(212) 854-1754
Phone: 212-304-5606
Columbia University In 1897, the university moved from Forty-ninth Street and Madison Avenue, where it...
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Philadelphia, Pennsylvania 19104
Phone: 215-615-4452
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Philadelphia, PA
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