Study of Reduced Anti-coagulation/Anti-platelet Therapy in Patients With the HeartMate II Left Ventricular Assist System (LVAS) (TRACE)

Inclusion Criteria:

- HeartMate II Left Ventricular Assist Device (LVAD) patient

- Patient has signed an informed consent for data collection.

- Patient was discharged, or is being discharged, from the hospital after their initial
LVAD implant surgery.

- Patient:

- at time of enrolling in study, is currently on, with the intention of being
maintained on reduced anti-thrombotic therapy (RT) for chronic long-term
management.

OR

-- On or after January 1, 2011 patient was being maintained on, or had been initiated with
the intention of being maintained on, reduced anti-thrombotic therapy (RT) for chronic
long-term management; but where RT was subsequently discontinued due to an adverse event or
transplant, explant, or death.

Exclusion Criteria:

- Patients under acute management of anti-thrombotic agents before a final decision on
long term antithrombotic strategy.

- Patients requiring a legal representative to sign consent form, rather than
themselves.

- Patient is being managed on other anti-thrombotic agents