A Long-Term Safety And Tolerability Extension Study Of Bapineuzumab In Alzheimer Disease Patients



Status:Terminated
Conditions:Alzheimer Disease
Therapuetic Areas:Neurology
Healthy:No
Age Range:51 - 90
Updated:4/21/2016
Start Date:December 2009
End Date:November 2012

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A Phase 3 Extension, Multicenter, Long Term Safety And Tolerability Trial Of Bapineuzumab (Aab 001, Eln115727) In Subjects With Alzheimer Disease Who Are Apolipoprotein E 4 Carriers And Participated In Study 3133k1-3001-us Or Study 3133k1-3001-ww.

The purpose of this study is to assess the long-term safety and tolerability of bapineuzumab
in subjects with Alzheimer Disease who participated in study 3133K1-3001(NCT00676143). Over
250 sites will participate in over 26 countries. Subjects will receive bapineuzumab. Each
subject's participation will last approximately 4 years.


Inclusion Criteria:

- Subject has completed study 3133K1-3001 (Week 78) and brain magnetic resonance
imaging (MRI) scan consistent with the diagnosis of Alzheimer Disease

- Mini-Mental Status Examination (MMSE) >=10 at screening

- Caregiver able to attend all clinic visits with subject

Exclusion Criteria:

- Any medical or psychiatric contraindication or clinically significant abnormality
that, in the investigator's judgment, will substantially increase the risk associated
with the subject's participation in and completion of the study or could preclude the
evaluation of the subject's response.

- Any significant brain MRI abnormality.

- Use of any investigational drugs or devices, other than bapineuzumab within the last
60 days prior to screening
We found this trial at
64
sites
Dallas, Texas 75214
1680
mi
from 98109
Dallas, TX
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1720 2nd Ave S
Birmingham, Alabama 35233
(205) 934-4011 
University of Alabama at Birmingham The University of Alabama at Birmingham (UAB) traces its roots...
2072
mi
from 98109
Birmingham, AL
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1000 Alpine
Boulder, Colorado 80304
303-443-7229
996
mi
from 98109
Boulder, CO
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100 West Gore St # 202
Orlando, Florida 32806
(407) 426-9299
Compass Research LLC Compass Research is a clinical research company dedicated to testing new medications...
2547
mi
from 98109
Orlando, FL
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5430 Fredericksburg Road
San Antonio, Texas 78229
210-377-2873
1780
mi
from 98109
San Antonio, TX
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3603 Paesanos Parkway
San Antonio, Texas 78231
210-614-4884
1775
mi
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San Antonio, TX
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Abington, Pennsylvania 19001
2370
mi
from 98109
Abington, PA
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Abington, Pennsylvania 19001
2369
mi
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Abington, PA
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Abington, Pennsylvania 19001
2369
mi
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Abington, PA
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Atlantis, Florida 33462
2698
mi
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Atlantis, FL
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Atlantis, Florida 33462
2696
mi
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Atlantis, FL
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Birmingham, Alabama 35294
2079
mi
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Birmingham, AL
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Boulder, Colorado 80304
995
mi
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Boulder, CO
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6918
mi
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Buenos Aires,
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2423
mi
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Charleston, SC
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171 Ashley Avenue
Charleston, South Carolina 29425
843-792-1414
Medical University of South Carolina The Medical University of South Carolina (MUSC) has grown from...
2422
mi
from 98109
Charleston, SC
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Columbus, Ohio 43210
2006
mi
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Columbus, OH
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Delray Beach, Florida 33445
2702
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Delray Beach, FL
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Denver, Colorado 80218
1021
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Denver, CO
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East Lansing, Michigan 48824
1855
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East Lansing, MI
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East Providence, Rhode Island 02914
2487
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East Providence, RI
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Eatontown, New Jersey 07724
2412
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Eatontown, NJ
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1713
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Elk Grove Village, IL
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2423
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Fairfield, CT
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Goodyear, Arizona 85395
1106
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Goodyear, AZ
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Greenwich, Connecticut 06830
2408
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Greenwich, CT
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Greenwich, Connecticut 06830
2408
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Greenwich, CT
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Hattiesburg, Mississippi 39401
2067
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Hattiesburg, MS
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Jenkintown, Pennsylvania 19046
2371
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Jenkintown, PA
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Kansas City, Missouri 64114
1507
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Kansas City, MO
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Lake Charles, Louisiana 70601
1954
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Lake Charles, LA
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Lawrenceville, Georgia 30046
2188
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Lawrenceville, GA
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Lawrenceville, Georgia 30046
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Lawrenceville, GA
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Little Rock, Arkansas 72205
1779
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Little Rock, AR
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MDR
LiverPool, New York 13088
2226
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LiverPool, NY
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Liverpool, New York 13088
2226
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Liverpool, NY
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2409
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Manchester, NJ
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North Charleston, South Carolina 29406
2422
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North Charleston, SC
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Norwalk, Connecticut 06851
2416
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Norwalk, CT
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2683
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Palm Beach Gardens, FL
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111 S 11th St
Philadelphia, Pennsylvania 19107
(215) 955-6000
Thomas Jefferson University Hospital Our hospitals in Center City Philadelphia share a 13-acre campus with...
2373
mi
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Philadelphia, PA
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1020 Walnut St
Philadelphia, Pennsylvania 19107
(215) 955-6000
Thomas Jefferson University We are dedicated to the health sciences and committed to educating professionals,...
2373
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Philadelphia, PA
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Phoenix, Arizona 85006
1115
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Phoenix, AZ
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1115
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Phoenix, AZ
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Phoenix, Arizona 85032
1106
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Phoenix, AZ
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Phoenix, Arizona 85050
1103
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Pittsfield, Massachusetts 01201
2382
mi
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Pittsfield, MA
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Port Charlotte, Florida 33952
2588
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Port Charlotte, FL
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Port Charlotte, Florida 33952
2589
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Port Charlotte, FL
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Portland, Oregon 97210
146
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Portland, OR
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149
mi
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Portland, OR
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Portland, Oregon 97225
147
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Portland, OR
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Raleigh, North Carolina 27607
2358
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Raleigh, NC
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Raleigh, North Carolina 27607
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Raleigh, NC
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Raleigh, North Carolina 27607
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Raleigh, NC
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Raleigh, North Carolina 27607
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San Antonio, Texas 78231
1776
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San Antonio, TX
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San Antonio, Texas 78258
1787
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San Francisco, California
681
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San Francisco, CA
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Sarasota, Florida 34243
2549
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Sarasota, FL
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1705
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Springfield, IL
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Springfield, Massachusetts 01104
2423
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Springfield, MA
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2521
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Tampa, FL
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Toms River, New Jersey 08755
2418
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Toms River, NJ
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