Treatment for Alcoholism and Post-Traumatic Stress Disorder (Naltrexone)

This study will evaluate naltrexone and cognitive-behavioral therapy treatments for alcohol
dependence and post-traumatic stress disorder (PTSD). Subjects will be randomly assigned a
6-month treatment of either: 1) naltrexone alone, 2) naltrexone with PTSD psychosocial
therapy, 3) a placebo with PTSD psychosocial therapy, or 4) placebo alone. An enhanced
medication management intervention will accompany all treatment conditions. Followup
assessments will be completed at 9 and 12 months after treatment.