An Inpatient Study Of The Efficacy, Safety, And Tolerability Of PF-02545920 In The Treatment Of Acute Exacerbation Of Schizophrenia



Status:Completed
Conditions:Schizophrenia
Therapuetic Areas:Psychiatry / Psychology
Healthy:No
Age Range:18 - 65
Updated:5/24/2018
Start Date:October 2010
End Date:August 2011

Use our guide to learn which trials are right for you!

A Phase 2, Multicenter, Double-blind, Randomized, Parallel Group, 4-week Inpatient Study To Evaluate The Safety And Efficacy Of Two Fixed Doses Of Pf-02545920 Compared To Placebo In The Treatment Of Acute Exacerbation Of Schizophrenia Using Risperidone As An Active Control

This study aims to evaluate whether PF-02545920 is safe and effective in the treatment of
acute exacerbation of schizophrenia during a 4-week inpatient treatment period. The study
will use the Positive and Negative Syndrome Scale (PANSS) to measure change in symptoms for
PF-02545920 compared to risperidone and placebo treatment.


Inclusion Criteria:

- Diagnosis of schizophrenia with acute exacerbation of illness

- The current acute exacerbation of schizophrenia must be less than 4 weeks duration
prior to the initial evaluation.

Exclusion Criteria:

- Subjects with evidence or history of clinically significant uncontrolled medical
illness

- Subjects with a current diagnosis of schizoaffective disorder, major depression,
bipolar disorder, or obsessive compulsive disorder.

- Subjects who meet Diagnostic and Statistical Manual-IV (DSM-IV)defined diagnostic
criteria for psychoactive substance dependence (excluding nicotine dependence) within
12 months of screening or DSM-IV defined substance abuse within 3 months prior to
screening.
We found this trial at
39
sites
88 Park Avenue
Hollis, New York 11423
2425
mi
from 91732
Hollis, NY
Click here to add this to my saved trials
Anaheim, California 92801
17
mi
from 91732
Anaheim, CA
Click here to add this to my saved trials
811 Juniper St NE
Atlanta, Georgia 30308
(404) 881-5800
Atlanta Center for Medical Research Welcome to the Atlanta Center for Medical Research, a leader...
1919
mi
from 91732
Atlanta, GA
Click here to add this to my saved trials
Austin, Texas 78731
1208
mi
from 91732
Austin, TX
Click here to add this to my saved trials
Austin, Texas 78745
1212
mi
from 91732
Austin, TX
Click here to add this to my saved trials
Austin, Texas 78754
1215
mi
from 91732
Austin, TX
Click here to add this to my saved trials
8043 Cooper Creek Boulevard Suite 107
Bradenton, Florida 34201
(941) 747-7900
Florida Clinical Research Center, LLC Led by Andrew J. Cutler, M.D., Florida Clinical Research Center,...
2143
mi
from 91732
Bradenton, FL
Click here to add this to my saved trials
DeSoto, Texas 75115
1223
mi
from 91732
DeSoto, TX
Click here to add this to my saved trials
Escondido, California 92025
82
mi
from 91732
Escondido, CA
Click here to add this to my saved trials
Escondido, California 92025
84
mi
from 91732
Escondido, CA
Click here to add this to my saved trials
Garden Grove, California 92845
20
mi
from 91732
Garden Grove, CA
Click here to add this to my saved trials
Hoffman Estates, Illinois 60169
1706
mi
from 91732
Hoffman Estates, IL
Click here to add this to my saved trials
Hoffman Estates, Illinois 60169
1706
mi
from 91732
Hoffman Estates, IL
Click here to add this to my saved trials
1786 Moon Lake Boulevard
Hoffman Estates, Illinois 60169
1705
mi
from 91732
Hoffman Estates, IL
Click here to add this to my saved trials
Houston, Texas 77024
1349
mi
from 91732
Houston, TX
Click here to add this to my saved trials
5314 Dashwood Drive
Houston, Texas 77081
1353
mi
from 91732
Houston, TX
Click here to add this to my saved trials
Kirkland, Washington 98033
964
mi
from 91732
Kirkland, WA
Click here to add this to my saved trials
10200 Northeast 132nd Street
Kirkland, Washington 98034
967
mi
from 91732
Kirkland, WA
Click here to add this to my saved trials
Lake Charles, Louisiana 70601
1469
mi
from 91732
Lake Charles, LA
Click here to add this to my saved trials
Lake Charles, Louisiana 70601
1471
mi
from 91732
Lake Charles, LA
Click here to add this to my saved trials
Little Rock, Arkansas 72201
1463
mi
from 91732
Little Rock, AR
Click here to add this to my saved trials
Long Beach, California 90806
23
mi
from 91732
Long Beach, CA
Click here to add this to my saved trials
Long Beach, California 90822
21
mi
from 91732
Long Beach, CA
Click here to add this to my saved trials
Maitland, Florida 32751
2183
mi
from 91732
Maitland, FL
Click here to add this to my saved trials
5797
mi
from 91732
Mannheim,
Click here to add this to my saved trials
101 The City Drive South
Orange, California 92868
714-456-7890
University of California, Irvine Medical Center We are UC Irvine Health. We are a devoted...
21
mi
from 91732
Orange, CA
Click here to add this to my saved trials
434 West Kennedy Boulevard
Orlando, Florida 32810
2181
mi
from 91732
Orlando, FL
Click here to add this to my saved trials
Paramount, California 90723
14
mi
from 91732
Paramount, CA
Click here to add this to my saved trials
8835 Vans Street
Paramount, California 90723
14
mi
from 91732
Paramount, CA
Click here to add this to my saved trials
Philadelphia, Pennsylvania 19139
2371
mi
from 91732
Philadelphia, PA
Click here to add this to my saved trials
Rockville, Maryland 20850
2274
mi
from 91732
Rockville, MD
Click here to add this to my saved trials
10330 Old Olive Street Road
Saint Louis, Missouri 63141
1562
mi
from 91732
Saint Louis, MO
Click here to add this to my saved trials
San Diego, California 92123
101
mi
from 91732
San Diego, CA
Click here to add this to my saved trials
24
mi
from 91732
Santa Ana, CA
Click here to add this to my saved trials
Torrance, California 90502
22
mi
from 91732
Torrance, CA
Click here to add this to my saved trials
Torrance, California 90505
24
mi
from 91732
Torrance, CA
Click here to add this to my saved trials
Washington, District of Columbia 20016
2278
mi
from 91732
Washington,
Click here to add this to my saved trials
Willingboro, New Jersey 08046
2389
mi
from 91732
Willingboro, NJ
Click here to add this to my saved trials
218 Sunset Road
Willingboro, New Jersey 08046
2389
mi
from 91732
Willingboro, NJ
Click here to add this to my saved trials