Pazopanib in Previously Treated Patients With Metastatic Renal Cell Carcinoma



Status:Archived
Conditions:Cancer
Therapuetic Areas:Oncology
Healthy:No
Age Range:Any
Updated:7/1/2011
Start Date:August 2008
End Date:November 2011

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A Phase II Trial of Pazopanib in Patients With Metastatic Renal Cell Carcinoma Previously Treated With Sunitinib or Bevacizumab


This is a Phase II, non-randomized, open-label, single-arm study in patients with metastatic
renal cell carcinoma who have received one prior targeted therapy with either sunitinib or
bevacizumab. The planned enrollment for this study is 60 patients.


All eligible patients will receive 800 mg of pazopanib orally each day continuously.
Patients will be re-evaluated for treatment response after 8 weeks of daily oral pazopanib
therapy. Response to therapy will be assigned using RECIST criteria (Section 6.0)
Patients who have objective response or stable disease will continue treatment with
evaluations every 8 weeks, until the time of tumor progression or intolerable
treatment-related side effects.


We found this trial at
19
sites
Chattanooga, Tennessee 37404
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Boca Raton, Florida 33486
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Boca Raton, FL
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166 Stoneridge Drive
Columbia, South Carolina 29210
803-461-3000
South Carolina Oncology Associates, PA South Carolina Oncology Associates (SCOA) is the only comprehensive cancer...
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Columbia, SC
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3840 Broadway
Fort Myers, Florida 33901
(239) 275-6400
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Fort Myers, FL
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Gainesville, Florida 30501
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Gainesville, FL
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1730
Lakeland, Florida 33805
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Lakeland, FL
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2501 N Orange Ave # 235
Orlando, Florida 32804
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Orlando, FL
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1099 5th Avenue North
St. Petersburg, Florida 33705
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St. Petersburg, FL
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Augusta, GA
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6410 Rockledge Dr #660
Bethesda, Maryland 20817
(301) 571-0019
Center for Cancer & Blood Disorders Widely recognized for its compassionate, expert care, the Center...
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Bethesda, MD
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5053 Wooster Rd
Cincinnati, Ohio 45226
(513) 751-2273
Oncology Hematology Care Our more than 60 physicians and advanced practice providers throughout neighborhood offices...
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Cincinnati, OH
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Grand Rapids, Michigan 49503
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Grand Rapids, MI
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Lewiston, Maine 04240
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Lewiston, ME
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Louisville, Kentucky 40207
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Louisville, KY
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250 25th Ave N, Ste 100
Nashville, Tennessee 37023
615-320-5090
Tennessee Oncology, PLLC Since 1976 Tennessee Oncology has been providing quality cancer care. In 2013,...
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Nashville, TN
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Omaha, NE
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Richmond, Virginia 23235
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Richmond, VA
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Saint Louis, Missouri 63141
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Saint Louis, MO
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San Francisco, California 94115
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San Francisco, CA
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