Children's Hospital of Philadelphia
South 34th Street
Philadelphia, Pennsylvania 19104
 215-590-1000 http://www.chop.edu/

Use our guide to learn which trials are right for you!

Since its start in 1855 as the nation's first hospital devoted exclusively to caring for children, The Children's Hospital of Philadelphia has been the birthplace for many dramatic firsts in pediatric medicine. The Hospital has fostered medical discoveries and innovations that have improved pediatric healthcare and saved countless children’s lives. Over 150 years of innovation and service to our patients, their families and our community, reflect an ongoing commitment to exceptional patient care.

We've found
402 trials
at this facility
Gastroenterology, Pharmacology / Toxicology Clinical Trial
X-linked Hypophosphatemia Disease Monitoring Program
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Pediatric Sepsis-induced MODS Clinical Trial
GM-CSF for Reversal of immunopAralysis in pediatriC sEpsis-induced MODS Study
Status: Enrolling, Phase IV
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Congenital Hyperinsulinism Clinical Trial
Open-label Trial Evaluating Efficacy and Safety of Dasiglucagon in Children With Congenital Hyperinsulinism
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Other Clinical Trial
Improving Family Meetings in the Pediatric Cardiac Intensive Care Unit
Status: Enrolling
Updated: 12/31/1969
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from
Philadelphia, PA
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Neurology Clinical Trial
SmarToyGym: Smart Detection of Atypical Toy-oriented Actions in At-risk Infants
Status: Enrolling
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Prader-Willi Syndrome Clinical Trial
Phase 3 Study of Intranasal Carbetocin (LV-101) in Patients With Prader-Willi Syndrome
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Family-centered Care in Pediatric Resuscitation Clinical Trial
Evaluation of Online Training Tools in Pediatric Resuscitation
Status: Enrolling
Updated: 12/31/1969
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from
Philadelphia, PA
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Attention Deficit Disorder With Hyperactivity Clinical Trial
Nutrient Intake in Children With Attention Deficit Hyperactivity Disorder
Status: Enrolling
Updated: 6/23/2005
mi
from
Philadelphia, PA
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Other Clinical Trial
The Pediatric Anesthesia Quality Improvement Project
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Oncology Clinical Trial
Biomarkers in Tumor Tissue Samples From Patients With Newly Diagnosed Neuroblastoma or Ganglioneuroblastoma
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Oncology Clinical Trial
Maintenance Chemotherapy or Observation Following Induction Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Ependymoma
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Musculoskeletal, Neurology, Oncology, Psychiatry / Psychology, Other Clinical Trial
Combination Chemotherapy in Treating Young Patients With Newly Diagnosed High-Risk Acute Lymphoblastic Leukemia
Status: Enrolling, Phase III
Updated: 2/3/2016
mi
from
Philadelphia, PA
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Dental / Maxillofacial Surgery, Neurology Clinical Trial
Genetics of Charcot Marie Tooth (CMT) - Modifiers of CMT1A, New Causes of CMT2
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Infusion Reactions Clinical Trial
Safety Study of Unlicensed, Investigational Cord Blood Units Manufactured by the NCBP for Unrelated Transplantation
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Hemophagocytic Lymphohistiocytosis Clinical Trial
Tocilizumab and Hemophagocytic Lymphohistiocytosis (HLH)
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Legg Calve Perthes Disease Clinical Trial
Multicenter Prospective Cohort Study on Current Treatments of Legg-Calvé-Perthes Disease
Status: Enrolling
Updated: 2/8/2018
mi
from
Philadelphia, PA
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Clinical Trial
The Chimerix CMX001 Registry
Status: Enrolling
Updated: 7/31/2017
mi
from
Philadelphia, PA
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Males With X-linked Myotubular Myopathy (XLMTM) Clinical Trial
A Medical Chart Review of Patients With X-Linked Myotubular Myopathy (XLMTM)
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Multiple Sclerosis Clinical Trial
Adherence in Pediatric Multiple Sclerosis
Status: Enrolling
Updated: 2/5/2015
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from
Philadelphia, PA
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Reproductive Clinical Trial
Craniofacial Microsomia: Longitudinal Outcomes in Children Pre-Kindergarten (CLOCK)
Status: Enrolling
Updated: 12/11/2015
mi
from
Philadelphia, PA
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Orthopedics / Podiatry, Reproductive Clinical Trial
The Treatment of Progressive Early Onset Spinal Deformities: A Multi-Center Outcome Study
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Oncology Clinical Trial
Pilot Study of Redirected Autologous T Cells Engineered to Contain Humanized Anti-CD19 in Patients With Relapsed or Refractory CD19+ Leukemia and Lymphoma Previously Treated With Cell Therapy
Status: Enrolling, Phase I
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Food Allergy Clinical Trial
Efficacy and Safety of Viaskin Milk in Children With IgE-Mediated Cow's Milk Allergy
Status: Enrolling, Phase I, II
Updated: 3/11/2016
mi
from
Philadelphia, PA
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Cardiology / Vascular Diseases Clinical Trial
Pediatric Pulmonary Hypertension Network (PPHNet) Informatics Registry
Status: Enrolling
Updated: 2/9/2018
mi
from
Philadelphia, PA
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Adolescent Idiopathic Scoliosis Clinical Trial
AIS Patient Positioning in EOS System®
Status: Enrolling
Updated: 11/30/2015
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Philadelphia, PA
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Hepatitis C Virus Infection Clinical Trial
A Registry for Adolescent and Pediatric Participants Who Received a Gilead Hepatitis C Virus Direct Acting Antiviral (DAA) in Gilead-Sponsored Chronic Hepatitis C Infection Trials
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Gastroenterology Clinical Trial
OMEGA: Outcome Measures in Eosinophilic Gastrointestinal Disorders Across the Ages
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Steroid Refractory Acute Graft Versus Host Disease Clinical Trial
UVADEX® and ECP for the Treatment of Pediatric Patients With Steroid Refractory Acute Graft Versus Host Disease
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Gastroenterology Clinical Trial
Domperidone Expanded Access Protocol for Patients With Gastrointestinal Disorders
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Oncology Clinical Trial
Combination Chemotherapy With or Without Temsirolimus in Treating Patients With Intermediate Risk Rhabdomyosarcoma
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Juvenile Idiopathic Arthritis Clinical Trial
Efficacy Study Of Tofacitinib In Pediatric JIA Population
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Rheumatic Joint Disease Clinical Trial
Observational Study of Pediatric Rheumatic Diseases: The CARRA Registry
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Cardiology / Vascular Diseases Clinical Trial
Quality of Pediatric Resuscitation in a Multicenter Collaborative
Status: Enrolling, Phase
Updated: 4/6/2018
mi
from
Philadelphia, PA
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Alexander Disease Clinical Trial
Natural History and Outcome Measures in Alexander Disease
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Cancer Survivor Clinical Trial
Carvedilol in Preventing Heart Failure in Childhood Cancer Survivors
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Pyruvate Dehydrogenase Complex Deficiency Clinical Trial
Trial of Dichloroacetate in Pyruvate Dehydrogenase Complex Deficiency:
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Neurology, Other Clinical Trial
Biobanking of Rett Syndrome and Related Disorders
Status: Enrolling, Phase
Updated: 4/18/2018
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from
Philadelphia, PA
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Endocrinology Clinical Trial
Microbiome, Antibiotics, and Growth Infant Cohort
Status: Enrolling, Phase
Updated: 12/31/1969
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from
Philadelphia, PA
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Neurology Clinical Trial
High-dose Erythropoietin for Asphyxia and Encephalopathy
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Adenovirus Clinical Trial
Expanded Access Protocol to Provide Brincidofovir for the Treatment of Serious Adenovirus Infection or Disease
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Dravet Syndrome Clinical Trial
An Open-Label Extension Trial to Assess the Long-Term Safety of ZX008 (Fenfluramine Hydrochloride HCl) Oral Solution in Children and Young Adults With Dravet Syndrome
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Cardiology / Vascular Diseases, Gastroenterology Clinical Trial
FibroScan™ in Pediatric Cholestatic Liver Disease (FORCE)
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Anterior Cruciate Ligament Reconstruction Clinical Trial
Pediatric ACL: Understanding Treatment Options
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Anemia, Sickle Cell Clinical Trial
STRIDE Biorepository
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Adenovirus Clinical Trial
A Multicenter Study to Obtain Retrospective Data for Subjects Previously Diagnosed With Adenovirus Infection to Serve as Matched Historical Controls for Study CMX001-304
Status: Enrolling
Updated: 2/25/2016
mi
from
Philadelphia, PA
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HIV INfections Clinical Trial
Connecting Youth and Young Adults to Optimize ART Adherence: YouTHrive Efficacy Trial
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Oncology Clinical Trial
Iobenguane I-131 or Crizotinib and Standard Therapy in Treating Younger Patients With Newly-Diagnosed High-Risk Neuroblastoma or Ganglioneuroblastoma
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Lumbar Puncture Clinical Trial
Ultrasound Assisted Lumbar Puncture in the Neonate
Status: Enrolling
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Nephrology / Urology, Other Clinical Trial
Prospective Research Rare Kidney Stones (ProRKS)
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Oncology, Other Clinical Trial
Phase II Study of Binimetinib in Children and Adults With NF1 Plexiform Neurofibromas
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Epilepsy Clinical Trial
Assessment of Pharmacokinetics and Safety of Diazepam Buccal Soluble Film in Pediatric Patients
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Clinical Trial
VX15/2503 in Treating Younger Patients With Recurrent, Relapsed, or Refractory Solid Tumors
Status: Enrolling, Phase I, II
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Intermittent Hypoxia Clinical Trial
Intermittent Hypoxia and Caffeine in Infants Born Preterm
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Primary Mitochondrial Myopathy Clinical Trial
A Trial to Evaluate the Safety and Efficacy of Elamipretide in Subjects With Primary Mitochondrial Myopathy Followed by an Open-Label Extension
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Bone Marrow Failure Syndromes Clinical Trial
Fludarabine Based RIC for Bone Marrow Failure Syndromes
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Philadelphia, PA
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NF type1 With Inoperable Plexiform Neurofibromas Clinical Trial
An Intermediate Access Protocol for Selumetinib for Treatment of Neurofibromatosis Type 1
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Immunology / Infectious Diseases, Oncology Clinical Trial
Selumetinib Sulfate in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Activating MAPK Pathway Mutations (A Pediatric MATCH Treatment Trial)
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Hematology, Immunology / Infectious Diseases, Oncology Clinical Trial
Vemurafenib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With BRAF V600 Mutations (A Pediatric MATCH Treatment Trial)
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Hematology, Immunology / Infectious Diseases, Oncology Clinical Trial
Olaparib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Defects in DNA Damage Repair Genes (A Pediatric MATCH Treatment Trial)
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Heart Defect, Congenital Clinical Trial
Xeltis Bioabsorbable Pulmonary Valved Conduit Early Feasibility Study
Status: Enrolling
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Nephrology / Urology Clinical Trial
Urological and Renal Disease Engaging Adolescents in Adherence Collaborative Trial
Status: Enrolling
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Immunology / Infectious Diseases Clinical Trial
Modified Measles Virus (MV-NIS) for Children and Young Adults With Recurrent Medulloblastoma or Recurrent ATRT
Status: Enrolling, Phase I
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Cardiology / Vascular Diseases Clinical Trial
Pharmacokinetic Study of Intranasal Dexmedetomidine in Pediatric Patients With Congenital Heart Disease
Status: Enrolling, Phase I
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Childhood Absence Epilepsy Clinical Trial
Long-Term Safety of Pharmaceutical Grade Synthetic Cannabidiol Oral Solution in Pediatric Participants With Treatment-Resistant Childhood Absence Seizures
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Advanced Cancer Clinical Trial
The PediQUEST Response Intervention Study
Status: Enrolling
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Immunology / Infectious Diseases Clinical Trial
Flu2Text: Text Message Reminders for 2nd Dose of Influenza Vaccine
Status: Enrolling
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Other Clinical Trial
Rare Diseases Clinical Research Network: Neurophysiological Correlates
Status: Enrolling, Phase
Updated: 4/18/2018
mi
from
Philadelphia, PA
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Gastroenterology, Pulmonary / Respiratory Diseases, Other Clinical Trial
Inhaled Tissue Plasminogen Activator for Acute Plastic Bronchitis
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Episodic Migraine Clinical Trial
A Study of Galcanezumab (LY2951742) in Participants 6 to 17 Years of Age With Episodic Migraine
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Sickle Cell Disease Clinical Trial
Hydroxyurea Adherence for Personal Best in Sickle Cell Disease (HABIT): Efficacy Trial
Status: Enrolling
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Fabry Disease Clinical Trial
Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of Migalastat in Pediatric Subjects (Aged 12 to
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Endocrinology, Gastroenterology Clinical Trial
Bionic Pancreas in Children With Hyperinsulinism and Post-Pancreatectomy Diabetes
Status: Enrolling
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Neurology, Other Clinical Trial
Aerobic Exercise for Concussion
Status: Enrolling
Updated: 12/31/1969
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from
Philadelphia, PA
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Other Clinical Trial
Multi-center Isoelectric EEG Study in Children Under General Anesthesia
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Hematology, Immunology / Infectious Diseases, Oncology Clinical Trial
Palbociclib in Treating Patients With Relapsed or Refractory Rb Positive Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Activating Alterations in Cell Cycle Genes (A Pediatric MATCH Treatment Trial)
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Oncology, Other Clinical Trial
Medication Adherence in Children, Adolescents and Adults With Neurofibromatosis Type 1 (NF1) on Clinical Treatment Trials
Status: Enrolling
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Psychiatry / Psychology Clinical Trial
A Pilot Efficacy and Implementation Study of the Strengths Intervention Project
Status: Enrolling
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Oncology Clinical Trial
Cisplatin and Combination Chemotherapy in Treating Children and Young Adults With Hepatoblastoma or Liver Cancer After Surgery
Status: Enrolling, Phase II, III
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Clinical Trial
This Study Will Investigate the Efficacy and Safety of A4250 in Children With PFIC 1 or 2
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Immunology / Infectious Diseases Clinical Trial
Alpha/Beta T and CD19+ Depleted Peripheral Stem Cells for Patients With Primary Immunodeficiencies
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Trauma Abdomen Clinical Trial
CEUS for Blunt Abdominal Trauma in Children
Status: Enrolling, Phase IV
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Hemophilia A Clinical Trial
Long-Term Safety and Efficacy of SPK-8011 in Males With Hemophilia A
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Tetralogy of Fallot Clinical Trial
Pediatric REPlAcement of the PulmonaRy ValvE in Tetralogy of Fallot -
Status: Enrolling
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Oncology Clinical Trial
A Phase 1b Study of PTC596 in Children With Newly Diagnosed Diffuse Intrinsic Pontine Glioma and High Grade Glioma
Status: Enrolling, Phase I
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Crohn Disease Clinical Trial
Pilot Study of Fundamental Modification of the Gut Microbiota in the Treatment of Refractory Crohn's Disease
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Infection Clinical Trial
Gastrointestinal Implications of Voriconazole Exposure
Status: Enrolling, Phase
Updated: 12/31/1969
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from
Philadelphia, PA
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Transplant Clinical Trial
Improving Medication Adherence in Adolescents Who Had a Liver Transplant
Status: Enrolling
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Epidermolysis Bullosa Clinical Trial
Phase III Efficacy and Safety Study of Oleogel-S10 in Epidermolysis Bullosa
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Acute Lymphoblastic Leukemia ALL Clinical Trial
Ribociclib in Combination With Everolimus and Dexamethasone in Relapsed ALL
Status: Enrolling, Phase I
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Diabetes Mellitus, Type 1 Clinical Trial
A Study to Assess the Safety and Tolerability of Different Doses of AG019 Administered Alone or in Combination With Teplizumab in Participants With Recently Diagnosed Type 1 Diabetes Mellitus (T1D)
Status: Enrolling, Phase I, II
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Peanut Allergy Clinical Trial
Follow-up of the EPITOPE Study to Evaluate Long-term Efficacy and Safety of DBV712 in Young Children
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Trigger Thumb Clinical Trial
Trigger Thumb Randomized Controlled Trial
Status: Enrolling
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Metachromatic Leukodystrophy (MLD) Clinical Trial
A Study of Intrathecal SHP611 in Participants With Late Infantile Metachromatic Leukodystrophy
Status: Upcoming, Phase II
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Type 1 Diabetes Mellitus Clinical Trial
A Study Comparing LY900014 to Insulin Lispro (Humalog) in Children and Adolescents With Type 1 Diabetes
Status: Upcoming, Phase III
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Oncology Clinical Trial
BGB-290 and Temozolomide in Treating Isocitrate Dehydrogenase (IDH)1/2-Mutant Grade I-IV Gliomas
Status: Upcoming, Phase I
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Gastroenterology Clinical Trial
CEUS Evaluation of Bowel Perfusion in Necrotizing Enterocolitis
Status: Upcoming, Phase III
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Oncology, Ophthalmology Clinical Trial
Adalimumab in JIA-associated Uveitis Stopping Trial
Status: Upcoming, Phase III
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Neurology Clinical Trial
Occipital Blocks for Acute Migraine
Status: Upcoming, Phase III
Updated: 12/31/1969
mi
from
Philadelphia, PA
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Septic Shock Clinical Trial
Life After Pediatric Sepsis Evaluation
Status: Upcoming
Updated: 9/11/2012
mi
from
Philadelphia, PA
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Obesity Clinical Trial
Intranasal Oxytocin and Food Intake in Obese Adolescents
Status: Upcoming, Phase II
Updated: 4/6/2018
mi
from
Philadelphia, PA
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