Upstate Pharmaceutical Research
30 Pointe Circle
Greenville, South Carolina 29615

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Upstate Pharmaceutical Research is a dedicated Phase I-IV research site, founded in 2000. Located in Greenville, SC, Upstate Pharmaceutical Research is very close to Patewood Memorial Hospital and St. Francis Hospital. Upstate Pharmaceutical Research staff has many years of combined research experience. We are dedicated to following Good Clinical Practice Guidelines and meeting all FDA requirements. PI and coordinators are certified by A.C.R.P. Our patients feel we care for them because we believe "patients first," and we continue to work hard, learn, and grow. Our PI is involved in true sense, which makes our center unique.

Upstate Pharmaceutical Research services include:

  • Four full-time coordinators submitting documents promptly
  • Study Manager software program to include database housing, accounting capabilities and patient tracking
  • Patient database of over 20,000
  • Referral base of over 12,000 from busy family practices
  • The ability to use central IRB's and prompt submission, less than a week
  • Dedicated recruitment specialist
  • Dedicated regulatory person
  • Experience with PK, sampling, time points, frequent spirometrys
  • We even work on Saturdays to accommodate our patients
  • We have several sub specialists, PI, and sub PI's include cardiovascular, Ob-Gyn, Rheumatology, GI, Psychiatry, Ortho, Podiatry, Neurology, and Dermatology
  • Compliance and Retention is our goal

Since 2000, Upstate Pharmaceutical Research has conducted over 100 studies in the following areas:

  • Allergic Rhinitis
  • Anticoagulation Studies
  • Asthma
  • Atrial Fibrillation
  • Bladder Disorders
  • BPH
  • COPD
  • Chronic Renal Insufficiency
  • Diabetes
  • Diabetic insulin inhalers
  • Diabetic Nephropathy
  • Gout
  • Hyperlipidemia
  • Hypertension
  • Insomnia
  • Menopause
  • Neuropathy
  • Obesity
  • Osteoarthritis
  • Organic impotence
  • Stem cell infusion

Ability to conduct studies in the following indications/areas:
Carpal tunnel, restless leg syndrome, rheumatoid arthritis, acid reflux, constipation, migraines, depression and anxiety, I.B.D, IBS, pain management. Specialty areas: pulmonary, cardiology, orthopedic, gynecology, and podiatry studies.

Previous and current sponsors/CRO's include:

    • Abbott
    • Arena
    • AstraZeneca
    • Aventis
    • Boehringer-Ingleheim
    • Bristol Myers Squibb
    • Covance
    • CTMS
    • Depomed
    • Eli Lilly
    • Elixir
    • Forest
    • GlaxoSmithKline
    • Icon
    • Mannkind
    • Merck
    • Mylan Bertek
    • Novartis
    • Omnicare
    • Osiris
    • Parexel
    • Pfizer
    • Pharmanet
    • PPD
    • Sepracor
    • Shionogi
    • Quintiles
    • Schering Plough
    • Takeda
    • Tap
    • UBC

Medical Criteria

Principal Investigator:
Krishna K. Pudi, MD is board certified in internal medicine. He has 16 years total of research experience. Dr. Pudi was the Medical Director of the Hospitalist Program at the Spartanburg Regional Hospital.

Dr. Keith Waters
Dr. Barbara Ray
Dr. Julian Williams

Affiliated Investigators
Dr. Ayub Merchant-Gastroenterology
Dr. Charles Thomas-Orthopedic
Dr. Richard Zatcoff-Podiatry
Dr. Madhavi Allu-Internal Medicine
Dr. Gonzalo Pares-Neurologist
Dr. Neeta Rana Ob-Gyn

Upstate Pharmaceutical Research

  • 4 Experienced Coordinators
  • Dedicated Dietician on Staff
  • Echo Technician
  • Dedicated Recruitment Specialist
  • Regulatory Document Person
  • Staff is certified with BCLS-CRC-ACLS
  • Experience with infusion treatment

Greenville County Population by Gender 2000

Total = 379,616 Male=184,782 (48.7%) Female=194,834 (51.3%)

Greenville County Population by Race 2000

American Indian & Alaskan Native
Native Hawaiian & Pacific Islander
Two or More Races

Upstate Pharmaceutical Research

Cardiology/Vascular Diseases
Immunology/Infectious Diseases
Pulmonary/Respiratory Diseases

10,000 sq. foot dedicated space Phase I-IV research facility and less than half a mile from Patewood Memorial Hospital: 30 Pointe Circle

  • Comfortable lounge areas accommodating patients for all-day studies, including beds and showers
  • Patient dining room and catered meals
  • 15 private exam rooms
  • 4 private offices for coordinators
  • 3 private rooms for monitors
  • Secure rooms for on-site record storage
  • Temperature controlled, secured storage rooms for drugs, separate secure storage for refrigerated drugs
  • Patient database and study management on Study Manager software system
  • State of the Art Stress Test
  • Pulmonary Function Lab with DLCO, body phlethysmography, 6 minute walk
  • Full Laboratory with -20 and -70 freezers
  • Holter & Event monitors experience
  • 24 hour ABP monitors experience
  • ECG
  • Brand new exercise lab with metabolic bicycle ergometer
  • State of the Art Cardiac 2-D echo
  • Refrigerated Centrifuge
  • New Phase 1 Unit with 10 beds and dedicated entertainment and relaxing rooms with personal computers on the way
  • Dedicated photo copy machine to monitors
  • Defibrillation and crash cart
  • Our center has access to MRI, CT, mammogram, and x-ray
  • Internet access

Betty Pudi, RN, BSN
Upstate Pharmaceutical Research
30 Pointe Circle
Greenville, SC 29615
(864)255-3544 (fax)

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