Research Tissue Bank
| Status: | Recruiting |
|---|---|
| Conditions: | Cancer, Hematology |
| Therapuetic Areas: | Hematology, Oncology |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 11/3/2018 |
| Start Date: | September 2007 |
| End Date: | June 2019 |
| Contact: | Rona S Weinberg, PhD |
| Email: | rweinberg@nybloodcenter.org |
| Phone: | (212) 570-3412 |
This study that will allow for the preservation and/or storage of a small portion one or more
of the following tissues:
- Peripheral blood
- Bone marrow
- Bone marrow biopsy
- A phlebotomized unit of blood
- Spleen cells
- Toenail clippings
This material will be used for the study of Myeloproliferative Disorders (MPD) by
researchers. The goals of this research study are to understand the causes of MPDs, how to
diagnose them more easily and how to treat them better. MPD is a disease affecting
hematopoietic stem cells. Hematopoietic stem cells are cells that make blood cells. These
stem cells grow in the center portion of the bones called bone marrow. Under some conditions,
these cells are also found in blood. There are several diseases, which are classified as MPD.
These include polycythemia vera (too many red blood cells), essential thrombocythemia (too
many platelets), and idiopathic myelofibrosis (abnormal blood cells and fibers build up in
the bone marrow). These syndromes carry a high risk of developing leukemia. It is important
to continue to learn more about these blood cancers and to learn more about the effectiveness
and potential side effects of various treatments.
of the following tissues:
- Peripheral blood
- Bone marrow
- Bone marrow biopsy
- A phlebotomized unit of blood
- Spleen cells
- Toenail clippings
This material will be used for the study of Myeloproliferative Disorders (MPD) by
researchers. The goals of this research study are to understand the causes of MPDs, how to
diagnose them more easily and how to treat them better. MPD is a disease affecting
hematopoietic stem cells. Hematopoietic stem cells are cells that make blood cells. These
stem cells grow in the center portion of the bones called bone marrow. Under some conditions,
these cells are also found in blood. There are several diseases, which are classified as MPD.
These include polycythemia vera (too many red blood cells), essential thrombocythemia (too
many platelets), and idiopathic myelofibrosis (abnormal blood cells and fibers build up in
the bone marrow). These syndromes carry a high risk of developing leukemia. It is important
to continue to learn more about these blood cancers and to learn more about the effectiveness
and potential side effects of various treatments.
Inclusion Criteria:
- Patients diagnosed with Philadelphia chromosome negative myeloproliferative disorders
(MPD) polycythemia vera (PV), idiopathic myelofibrosis (IM), and essential
thrombocythemia (ET) are eligible.
- Newly diagnose MPD patients as well as previously treated for a MPD are eligible.
- Signed informed consent is required from each patient at the time of enrollment.
Exclusion Criteria:
- Patients currently participating in experimental treatment arms of MPD-RC protocols,
or other experimental treatment protocols are not eligible during the period they are
on study.
We found this trial at
10
sites
Johns Hopkins The Johns Hopkins University opened in 1876, with the inauguration of its first...
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1 Gustave L Levy Pl # 271
New York, New York 10029
New York, New York 10029
(212) 241-6500
Principal Investigator: Lewis Silverman, MD
Mount Sinai Med Ctr Founded in 1852, The Mount Sinai Hospital is a 1,171-bed, tertiary-care...
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201 Presidents Circle
Salt Lake City, Utah 84108
Salt Lake City, Utah 84108
801) 581-7200
Principal Investigator: Josef Prachal, MD
University of Utah Research is a major component in the life of the U benefiting...
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2035 W Taylor St
Chicago, Illinois
Chicago, Illinois
(312) 996-4350
Principal Investigator: Damiano Rondelli, MD
University of Illinois at Chicago A major research university in the heart of one of...
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Palo Alto, California 94301
Principal Investigator: David Leibowitz, MD
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3451 Walnut St
Philadelphia, Pennsylvania 19104
Philadelphia, Pennsylvania 19104
1 (215) 898-5000
Principal Investigator: Elizabeth Hexner, MD
Univ of Pennsylvania Penn has a long and proud tradition of intellectual rigor and pursuit...
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Washington, District of Columbia 10065
Principal Investigator: Tsiporah Shore, MD
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Washington, District of Columbia 20057
Principal Investigator: Craig Kessler, MD
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