Preop Cooled Radiofrequency Ablation for Total Knee Replacement



Status:Recruiting
Conditions:Arthritis, Osteoarthritis (OA), Post-Surgical Pain
Therapuetic Areas:Musculoskeletal, Rheumatology
Healthy:No
Age Range:65 - Any
Updated:3/30/2019
Start Date:March 26, 2019
End Date:October 2020
Contact:Jennifer Cheng
Email:chengj@hss.edu
Phone:6467146870

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A Pilot Study on the Utility of Cooled Radiofrequency Ablation in Patients Prior to Total Knee Arthroplasty

Total knee replacement surgery is commonly performed for patients suffering from severe knee
osteoarthritis. However, 20% of patients continue to experience pain after surgery. There is
currently no standardized pain management protocol for pain after total knee replacement.
Cooled radiofrequency ablation has been used successfully to alleviate spin-related pain and
has recently been approved by the FDA to treat chronic knee arthritic pain. This pilot study
aims to collect preliminary data on the use of cooled radiofrequency ablation in patients
undergoing total knee replacement.

The number of patients who undergo total knee replacement is rising significantly. However,
many of these patients are dissatisfied with the results, because they continue to experience
pain postoperatively. This pain can be debilitating and can also be associated with decreased
quality of life. Given the increasing number of patients undergoing total knee replacement
and a dissatisfaction rate of 8-44%, improvements must be made in pain management protocols
to help decrease pain in the immediate postoperative period following total knee replacement.
Cooled radiofrequency ablation is a procedure that uses water-cooled technology to denervate
the sensory nerves. It is widely used in the spine and is increasingly being used in the knee
to treat osteoarthritis. Existing studies have shown that it can significantly reduce pain in
patients with chronic osteoarthritis. In terms of its potential benefit as a preoperative
measure to minimize postoperative pain, the literature is sparse. Results from this study
will be used to generate hypotheses and power for future studies.

Inclusion Criteria:

- Patients undergoing unilateral primary total knee replacement for osteoarthritis

- Pain >6 (on a scale of 0-10)

- Body mass index: 21-35 kg/m2

Exclusion Criteria:

- Age <65 years

- Patients who are wheelchair bound

- History of inflammatory arthritis or rheumatic disease

- Body mass index <21 or >35 kg/m2

- Chronic opioid use

- Pregnant women

- Non-English speaking
We found this trial at
1
site
535 E 70th St
New York, New York 10021
(212) 606-1000
Hospital for Special Surgery Founded in 1863, Hospital for Special Surgery is the nation
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