A Randomized Controlled Trial of an Antiretroviral Treatment Adherence Intervention for HIV+ African Americans
| Status: | Recruiting |
|---|---|
| Conditions: | HIV / AIDS |
| Therapuetic Areas: | Immunology / Infectious Diseases |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 3/28/2019 |
| Start Date: | December 1, 2017 |
| End Date: | July 1, 2021 |
| Contact: | Laura Bogart, PhD |
| Email: | lbogart@rand.org |
| Phone: | (310) 393-0411 |
Project Rise is a randomized controlled trial (RCT) of an innovative, culturally congruent
treatment education (TE) intervention for African Americans with HIV that targets cultural
and social issues contributing to health disparities.
treatment education (TE) intervention for African Americans with HIV that targets cultural
and social issues contributing to health disparities.
Project Rise is a randomized controlled trial (RCT) of an innovative, culturally congruent
treatment education (TE) intervention for African Americans with HIV that targets cultural
and social issues contributing to health disparities. TE facilitates patient navigation
through the medical system and provides treatment education and client-centered counseling to
improve adherence and retention in care. TE targets structural issues in healthcare and
patients' lives by advocating to providers to improve patient-provider relationships,
recommending changes in treatment and/or providers, and referring patients to mental health
and social services.
A total of 350 Black participants will be recruited through APLA Health and randomly assigned
to the intervention or usual care control group (175 per group). Adherence will be
electronically monitored daily (and downloaded bi-monthly) from baseline to 13-months
post-baseline. Viral load will be assessed through venipuncture at baseline and 6- and
13-months post-baseline. It is hypothesized that the intervention group will show better
adherence and have a greater likelihood of suppressed viral load than the control group over
time.
treatment education (TE) intervention for African Americans with HIV that targets cultural
and social issues contributing to health disparities. TE facilitates patient navigation
through the medical system and provides treatment education and client-centered counseling to
improve adherence and retention in care. TE targets structural issues in healthcare and
patients' lives by advocating to providers to improve patient-provider relationships,
recommending changes in treatment and/or providers, and referring patients to mental health
and social services.
A total of 350 Black participants will be recruited through APLA Health and randomly assigned
to the intervention or usual care control group (175 per group). Adherence will be
electronically monitored daily (and downloaded bi-monthly) from baseline to 13-months
post-baseline. Viral load will be assessed through venipuncture at baseline and 6- and
13-months post-baseline. It is hypothesized that the intervention group will show better
adherence and have a greater likelihood of suppressed viral load than the control group over
time.
Inclusion Criteria:
- HIV-positive
- 18 years of age or older
- Self-identified as African American/Black
- Been prescribed antiretroviral therapy (ART) in the past 12 months
- Self-reported adherence problems (i.e. missed at least 1 ART dose in the past month)
and/or detectable viral load
- Willing to use Medication Events Monitoring System (MEMS) for electronic adherence
monitoring.
Exclusion Criteria:
- HIV-negative
- 17 years of age or younger
- Not self-identified as African American/Black, not on antiretroviral therapy (ART) or
not prescribed ART therapy in the last than 12 months
- No self-reported adherence problems and/or no detectable viral load
- Not willing to use Medication Events Monitoring System (MEMS) for electronic adherence
monitoring.
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