The Peer-Based Retention of People Who Use Drugs in Rural Research



Status:Not yet recruiting
Healthy:No
Age Range:18 - Any
Updated:3/23/2019
Start Date:May 1, 2019
End Date:May 1, 2020
Contact:Todd Korthuis, MD, MPH
Email:korthuis@ohsu.edu
Phone:503-494-8044

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The purpose of this study is to, through several aims, test the effectiveness of peer-driven
intervention and inform methods to optimize engagement in research in people who use drugs
(PWUD) in rural America.

This study builds on the National Rural Opioids Initiative (NROI), a multi-state consortium
studying access to care, overdose, and infectious consequences of opioid use disorder (OUD)
in Rural America. It includes counties in rural Oregon and Appalachian Kentucky and Ohio with
high rates of drug overdose.

Aim 1: Conduct a randomized trial to evaluate the effectiveness of a peer-driven study
retention intervention for retaining PWUD in Kentucky, Ohio, and Oregon Rural Opioid
Initiative sites.

Aim 2: Elicit preferences of PWUD in the Kentucky, Ohio, and Oregon Rural Opioid Initiative
sites Aim 2a: Administer baseline survey of discrete choice experiment preferences for
participating in clinical trials of potential medical innovations (e.g. new treatments for
OUD, HIV, and HCV vaccination). Aim 2a will be accomplished as part of the NROI studies. The
data will then be merged for PROUD-R² analyses.

Aim 2b: Compare participant survey preferences regarding willingness to participate in
clinical trials at baseline, 6, and 12 months.

Aim 3: Explore participant perceptions of clinical research participation and retention among
PWUD in rural America.

Inclusion Criteria:

- NROI eligibility criteria: Participants are eligible to enroll in the NROI if they 1)
live in the study area, 2) have recently injected drugs or report opioid use to get
high without injection, and 3) are age 18 or older.

NROI participants enrolled after April 2019 are eligible to participate in this study if
they successfully refer at least on other participant within 3 months of NROI enrollment,
or are a part of a respondent-driven sampling chain. No eligible participants are excluded.

Exclusion Criteria:

- Under 18 years of age
We found this trial at
3
sites
Lexington, Kentucky
859) 257-9000
Phone: 859-218-2090
University of Kentucky The University of Kentucky is a public, land grant university dedicated to...
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201 Dowman Dr
Atlanta, Georgia 30303
(404) 727-6123
Emory University Emory University, recognized internationally for its outstanding liberal artscolleges, graduate and professional schools,...
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281 W. Lane Ave
Columbus, Ohio 43210
(614) 292-6446
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