A Study to Evaluate SAGE-217 in Adult Subjects With Major Depressive Disorder



Status:Recruiting
Conditions:Depression, Depression, Major Depression Disorder (MDD)
Therapuetic Areas:Psychiatry / Psychology, Pulmonary / Respiratory Diseases
Healthy:No
Age Range:18 - 75
Updated:4/4/2019
Start Date:February 27, 2019
End Date:April 2021
Contact:Timothy Mariano, MD, PhD, MSc
Email:timothy.mariano@sagerx.com
Phone:(617) 949-5588

Use our guide to learn which trials are right for you!

A Phase 3, Open-Label, 1-Year Study of the Safety, Tolerability, and Need for Re-Treatment With SAGE-217 in Adult Subjects With Major Depressive Disorder

This is a phase 3, open-label, 1-year study of the safety, tolerability, and need for
re-treatment with SAGE-217 in adult subjects with major depressive disorder


Inclusion Criteria:

1. Subject has a diagnosis of MDD as diagnosed by SCID-5-CT, with symptoms that have been
present for at least a 4-week period.

2. Subject is in good physical health and has no clinically significant findings, as
determined by the Investigator, on physical examination, 12-lead ECG, or clinical
laboratory tests.

Exclusion Criteria:

1. Subject has attempted suicide associated with the current episode of MDD.

2. Subject has a medical history of bipolar disorder, schizophrenia, and/or
schizoaffective disorder.

3. Subject has had vagus nerve stimulation, electroconvulsive therapy, or has taken
ketamine within the current major depressive episode.
We found this trial at
27
sites
Chicago, Illinois 60612
?
mi
from
Chicago, IL
Click here to add this to my saved trials
Albuquerque, New Mexico 87109
?
mi
from
Albuquerque, NM
Click here to add this to my saved trials
Austin, Texas 78723
?
mi
from
Austin, TX
Click here to add this to my saved trials
Bellevue, Washington 98007
?
mi
from
Bellevue, WA
Click here to add this to my saved trials
Bradenton, Florida 34201
?
mi
from
Bradenton, FL
Click here to add this to my saved trials
Brandon, Florida 33511
?
mi
from
Brandon, FL
Click here to add this to my saved trials
Brooklyn, New York 11235
?
mi
from
Brooklyn, NY
Click here to add this to my saved trials
Costa Mesa, California 92626
?
mi
from
Costa Mesa, CA
Click here to add this to my saved trials
Cromwell, Connecticut 06416
?
mi
from
Cromwell, CT
Click here to add this to my saved trials
Dallas, Texas 75251
?
mi
from
Dallas, TX
Click here to add this to my saved trials
Dothan, Alabama 36303
?
mi
from
Dothan, AL
Click here to add this to my saved trials
Lakeland, Florida 33805
?
mi
from
Lakeland, FL
Click here to add this to my saved trials
Lincoln, Nebraska 68526
?
mi
from
Lincoln, NE
Click here to add this to my saved trials
Miami, Florida 33155
?
mi
from
Miami, FL
Click here to add this to my saved trials
Mount Kisco, New York 10549
?
mi
from
Mount Kisco, NY
Click here to add this to my saved trials
New York, New York 10029
?
mi
from
New York, NY
Click here to add this to my saved trials
Norristown, Pennsylvania 19403
?
mi
from
Norristown, PA
Click here to add this to my saved trials
Omaha, Nebraska 68114
?
mi
from
Omaha, NE
Click here to add this to my saved trials
Pensacola, Florida 32502
?
mi
from
Pensacola, FL
Click here to add this to my saved trials
Princeton, New Jersey 08540
?
mi
from
Princeton, NJ
Click here to add this to my saved trials
Roswell, Georgia 30076
?
mi
from
Roswell, GA
Click here to add this to my saved trials
Saint Charles, Missouri 63304
?
mi
from
Saint Charles, MO
Click here to add this to my saved trials
Salem, Oregon 97301
?
mi
from
Salem, OR
Click here to add this to my saved trials
San Antonio, Texas 78229
?
mi
from
San Antonio, TX
Click here to add this to my saved trials
Shreveport, Louisiana 71101
?
mi
from
Shreveport, LA
Click here to add this to my saved trials
Tampa, Florida 33613
?
mi
from
Tampa, FL
Click here to add this to my saved trials
Woodstock, Vermont 05091
?
mi
from
Woodstock, VT
Click here to add this to my saved trials