Next-Generation Pre-Operative Targeting for Thalamic DBS in the Treatment of Tremor



Status:Not yet recruiting
Healthy:No
Age Range:18 - Any
Updated:3/16/2019
Start Date:April 2019
End Date:December 2020
Contact:Kendra J Brown, MPH, CCRP
Email:Brown.Kendra@mayo.edu
Phone:(904) 953-7755

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Transform the Practice: Next-Generation Pre-Operative Targeting for Thalamic DBS in the Treatment of Tremor

Researchers are investigating improved methods of targeting deep brain stimulators for
treatment of essential tremor relying on brain connectivity measures derived from MRI.


Inclusion Criteria:

- Diagnosis of refractory essential tremor scheduled for unilateral thalamic deep brain
stimulator placement

- Age ≥ 18 years

Exclusion Criteria:

- Prior deep brain stimulator, stereotactic radiosurgery, or focused ultrasound
procedure for treatment of tremor

- Presence of concomitant movement disorder (e.g. Parkinson's disease, dystonia, etc.)

- Known pre-existing structural brain abnormality (e.g, infarction, tumor, prior brain
surgery, etc.)

- Contraindication to 3 Tesla brain MRI (e.g. incompatible implanted device)

- Pregnant
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4500 San Pablo Rd S
Jacksonville, Florida 32224
(904) 953-2000
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