Association Between Cancer and Sarcoidosis



Status:Recruiting
Conditions:Cancer, Cancer, Endocrine
Therapuetic Areas:Endocrinology, Oncology
Healthy:No
Age Range:18 - Any
Updated:2/22/2019
Start Date:February 5, 2019
End Date:May 5, 2021
Contact:Mehdi Mirsaeidi, MD
Email:msm249@miami.edu
Phone:(305)243-9227

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Outcome Study of Sarcoidosis: a New Paraneoplastic Syndrome in Patient With Cancer

Development of cancer following sarcoidosis has been studied in the past, but, little is
known about the development of sarcoidosis following cancer. Investigators proposed an
association between cancer and sarcoidosis previously. Investigators suggested that
sarcoidosis could be a paraneoplastic disease.

The current project is a comprehensive study of paraneoplastic sarcoidosis disease.

The aim of the study is to find an association between sarcoidosis and cancer and to
determine the outcome of sarcoidosis in patients with cancer.

This is a retrospective single-center, observational study for collecting data on patients
with sarcoidosis and cancer in UMH and Sylvester Cancer Center. The study initially involves
populating sarcoidosis patients seen at UMH and Sylvester Cancer Canter during the study
period. This will add our knowledge about the characteristics of this novel paraneoplastic
syndrome and its effects on prognosis of sarcoidosis and cancer. Investigators will also
generate relevant hypotheses for future mechanistic studies.

Results of this study will be of interest to physicians, administrative and public health
authorities.

The purpose of this study is to develop a clinical dataset of sarcoidosis patients with a
diagnosis of cancer who are categorized by date of birth, sex, race/ethnicity, clinical
information, laboratory and imaging information, time of sarcoidosis onset, cancer type and
treatment, time of cancer diagnosis, stage and grade.

A clinical database of sarcoidosis patients with cancer that can be utilized by the
University of Miami faculty, fellows and their collaborators to investigate the relationship
between sarcoidosis and cancer will be made.

Inclusion Criteria:

- Clinical diagnosis of Sarcoidosis following cancer

- Granulomatous reaction must be proven by pathology

Exclusion Criteria:

. Aged younger than 18 years old.
We found this trial at
3
sites
1400 NW 12th Ave
Miami, Florida 33136
(305) 689-5511
Phone: 240-383-7539
University of Miami Hospital The University of Miami changed the face of modern health care...
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1601 Northwest 12th Avenue
Miami, Florida 33136
(305) 243-6545
Principal Investigator: Mehdi Mirsaeidi, MD
Phone: 305-243-2568
University of Miami Miller School of Medicine The University of Miami Leonard M. Miller School...
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Miami, Florida 33136
Phone: 240-383-7539
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