Same-session MR-only Simulation and Treatment With MRI-guided Adaptive Palliative RadioTherapy



Status:Not yet recruiting
Conditions:Cancer, Cancer, Gastrointestinal
Therapuetic Areas:Gastroenterology, Oncology
Healthy:No
Age Range:18 - Any
Updated:3/16/2019
Start Date:March 31, 2019
End Date:April 30, 2020
Contact:Hyun Kim, M.D.
Email:kim.hyun@wustl.edu
Phone:314-362-8502

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Pilot Study of Same-session MR-only Simulation and Treatment With MRI-guided Adaptive Palliative RadioTherapy (MAP-RT)

This proposed study is unique in that patients will not undergo computed tomography (CT)
simulation at any point during their treatment course and will instead have same-session
magnetic resonance (MR)-only simulation and treatment planning, on-table, using the adaptive
radiotherapy (ART) workflow. In this manner, patients requiring urgent treatment could
initiate treatment as early as the day of initial radiation oncology consultation.


Inclusion Criteria:

- Diagnosis of malignancy (biopsy proven or high clinical suspicion with urgent/emergent
clinical indications for palliative RT)

- Requires delivery of palliative radiation therapy for the treatment of painful
metastasis, hemoptysis, gastrointestinal bleeding, pelvic bleeding, or superior vena
cava syndrome/bulky mediastinal disease.

- At least 18 years of age.

- Able to understand and willing to sign an IRB-approved written informed consent
document.

Exclusion Criteria:

- Pregnant. Patients of childbearing potential must have a negative pregnancy test
within 14 days of study entry.

- Medical contraindication to undergoing MR imaging.
We found this trial at
1
site
660 S Euclid Ave
Saint Louis, Missouri 63110
(314) 362-5000
Principal Investigator: Hyun Kim, M.D.
Phone: 314-362-8502
Washington University School of Medicine Washington University Physicians is the clinical practice of the School...
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Saint Louis, MO
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