A Study to Evaluate BMS-986165 Tablet Formulation Relative to BMS-986165 Capsule Formulation and the Effect of a High-Fat/ High-Calorie Meal and Increased Gastric pH on the BMS-986165 Tablet Formulation

Inclusion Criteria:

- Patients must be willing and able to complete all study-specific procedures and visits

- Healthy patients, as determined by no clinically significant deviation from normal in
medical history, physical examination, electrocardiogram, and clinical laboratory
determinations

- Body mass index (BMI) of 18 to 32 kg/m2, inclusive, at screening

- Normal renal function at screening

Exclusion Criteria:

- Women of childbearing potential not using an effective contraceptive method or are
breastfeeding

- Any significant acute or chronic medical illness

- History of chronic headaches, defined as occurring 15 days or more a month, over the
previous 3 months

- History of headaches related to caffeine withdrawal, including energy drinks

- History of syncope, orthostatic instability, or recurrent dizziness

- Active TB requiring treatment or documented latent TB within the previous 3 years

Other protocol defined inclusion/exclusion criteria could apply.