5-Cog Battery for Detecting Cognitive Impairment and Dementia



Status:Not yet recruiting
Conditions:Cognitive Studies, Cognitive Studies, Cognitive Studies, Cognitive Studies, Neurology
Therapuetic Areas:Neurology, Psychiatry / Psychology
Healthy:No
Age Range:65 - Any
Updated:1/31/2019
Start Date:April 2019
End Date:August 2022
Contact:Project Manager
Email:emmeline.ayers@einstein.yu.edu
Phone:718-430-3835

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5-Cog Battery to Improve Detection of Cognitive Impairment and Dementia

Despite the availability of numerous cognitive assessment tools, cognitive impairment related
to dementia is frequently under-diagnosed in primary care settings. The investigators have
developed a 5-minute cognitive screen (5-Cog) coupled with a decision tree to overcome the
technical, cultural and logistic barriers of current cognitive screens to improve dementia
care in primary care patients with cognitive concerns.

Despite the availability of numerous cognitive assessment tools, cognitive impairment related
to dementia is frequently under-diagnosed in primary care settings, and is a more prevalent
problem among older African-Americans and Hispanics than among older whites. Missed detection
delays treatment of reversible conditions as well as provision of support services and
critical planning. To overcome the technical, cultural and logistic barriers of current
cognitive screens and dementia care in primary care settings the investigators have developed
a 5-minute cognitive screen (5-Cog) coupled with a decision tree to identify persons at high
risk of developing dementia in multi-ethnic primary care populations.

The 5-Cog includes the Picture based Memory Impairment Screen (PMIS), Motoric Cognitive Risk
syndrome (MCR), and a brief non-memory picture based test (Symbol Match). The cognitive
assessment will sort patients with 'cognitive impairment' from those with 'no cognitive
impairment'. It is coupled with a decision tree to guide clinicians through the follow up
based on results of the 5-Cog.

The primary objective is to test the ability of the 5-Cog and decision tree paradigm to
improve dementia care in primary care patients with cognitive concerns.

The investigators propose a single-blind, randomized clinical trial (RCT) in 1,200 older
primary care patients with cognitive concerns who will be randomized to receive the 5-Cog
(intervention group) or a 5-minute health literacy and grip assessment (active control
group). Non-physicians will administer the intervention and control assessments in primary
care sites and will provide results for both arms to the treating physician with a decision
tree follow up guide based on the results of the assessments.

Inclusion Criteria:

1. Age 65 and older.

2. Presence of cognitive or memory concerns expressed by patient, caregiver, health care
provider or other source who knows the patient.

3. Registered as patient at Montefiore Medical Center and have a primary care doctor
appointment that day.

4. Able to hear and see well enough to complete intervention or control assessments.

5. English or Spanish speaking.

Exclusion Criteria:

1. Prior diagnosis of dementia or MCI as ascertained by ICD-10 codes or the documentation
of prescription for anti-dementia medications in EMR. Patients with a diagnosis
containing any of the following terms will be excluded:

1. "Dementia"

2. "Mild Cognitive Impairment"

3. "Alzheimer's Disease"

4. "Creutzfeldt-Jakob Disease"

5. "Major Neurocognitive Disorder"

6. "Minor Neurocognitive Disorder"

Patients with any of the following medications documented in their EMR will be
excluded (generic = brand):

1. Donepezil = Aricept

2. Memantine = Namenda

3. Rivastigmine = Exelon

4. Galantamine = Razadyne

5. Donepezil and Memantine = Namzaric

2. Adults who are permanent residents of a nursing facility.

3. Patients who do not speak English or Spanish.

4. Patients who are not seeing a primary care physician at the clinic that day.

5. Patients who are blind or deaf or cannot hear loud voice even with hearing aids.
We found this trial at
1
site
1300 Morris Park Ave
Bronx, New York 10461
(718) 430-2000
Phone: 718-430-3835
Albert Einstein College of Medicine The Albert Einstein College of Medicine of Yeshiva University is...
?
mi
from
Bronx, NY
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