Creation of a Digital Heart Failure Registry Using a Novel Mobile Health Platform: HUGO-HF

Heart failure is the most common cause of mortality and morbidity in the United States and in
Western Europe. It is a complex and chronic illness, and patient journeys vary considerably.
However, to date, guidance about how to best treat patients has relied on large clinical
international trials that do not represent contemporary patients and only include snapshots
of the syndrome—at times when the patients interact with the health care system.
Additionally, patient participation in clinical research in the US is extremely low,
approximated at 3% in cancer and far lower for disease states such as heart failure.

One of the key reasons for this is a lack of patient engagement and trust in the research
enterprise, especially among the elderly and minorities, groups that are disproportionally
impacted by heart failure. To address this, the investigators plan to test a novel
patient-powered, smartphone-based mobile health platform (called Hugo) developed at Yale
School of Medicine for real-world surveillance of patient reported outcomes in heart failure
patients treated at 3 Major Academic Medical Centers. Participants will then be queried about
specific symptoms and health conditions at enrollment and prespecified time points for 2
years. The subgroup of participants who own devices that track their activity data will have
the option of syncing them to this mobile health platform to provide additional insights into
their health and health outcomes. Additionally, participants will have the option to learn
about opportunities to participate in heart failure clinical research. This digital registry
will also allow seamless integration of patient reported outcomes, electronic health record
(EHR) data, and pharmacy information into data collection.

Overall, the aim for this study is to create a digital registry using a novel patient
centered mobile health platform of heart failure patients across large health care systems
that allows investigators to engage patients in an entirely novel manner.

Inclusion Criteria:

- Age> 18 Years

- English Speaking

- Diagnosis of heart failure

- Participant is willing and able to read and sign consent and participate in study

- Participant has an email account

Exclusion Criteria:

- Unable to participate in registry