Age-independent Decline in Manual Dexterity of Middle-aged and Older Adults



Status:Not yet recruiting
Conditions:Healthy Studies
Therapuetic Areas:Other
Healthy:No
Age Range:50 - 89
Updated:1/16/2019
Start Date:December 2019
End Date:July 2025
Contact:Roger Enoka, PhD
Email:enoka@colorado.edu
Phone:3034927232

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The objective of the clinical trial is to evaluate the mediating influence of force control
on the pegboard times of adults (50-89 years) who are stratified into groups of faster and
slower pegboard times. The hypothesis is that practice of either a pegboard test or a
force-control task will reduce pegboard times, but the decrease will be greater and less
similar after the two practice interventions for the slower group of participants. The
outcomes are expected to demonstrate that force control is a modifiable mediator of pegboard
times for this cohort, but the effect will be stronger for the group with faster pegboard
times.

The study will involve a randomized, cross-over design with a one-week washout between arms.
The two arms (3 weeks each) will comprise practice of the grooved pegboard test and practice
of steady contractions while lifting and lowering light loads with a hand muscle.
Randomization into practice order will be accomplished with a block approach (block size = 4)
for each of the two groups. The outcome assessors will be blinded to practice order. The
outcomes will comprise three tests of manual dexterity and the measurement of force control
during submaximal contractions. The outcomes will be obtained before and after the six
sessions in each practice arm.

Inclusion Criteria:

- Able to read, write, and speak English

- Able to arrange transportation to the Boulder campus

Exclusion Criteria:

- Cognitive impairment

- Major psychiatric condition

- Unstable depressive disorder

- Progressive neurological, muscular, cardiovascular, or skeletal disorder

- Chronic pain condition

- Currently taking medication known to influence neuromuscular function

- Recent hospitalization

- Unable to attend 12 practice sessions in 6 weeks
We found this trial at
1
site
Boulder, Colorado 80309
(303) 492-1411
Phone: 303-492-7232
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