Predicting Cardiometabolic Risk in Mild-to-Moderate Obstructive Sleep Apnea: Inflammation vs. Apnea/Hypopnea Index



Status:Enrolling by invitation
Conditions:Insomnia Sleep Studies, Pulmonary, Pulmonary
Therapuetic Areas:Psychiatry / Psychology, Pulmonary / Respiratory Diseases
Healthy:No
Age Range:18 - Any
Updated:1/5/2019
Start Date:March 1, 2017
End Date:December 2019

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The purpose of the study is to compare the relative contribution of systemic inflammation vs.
Obstructive Sleep Apnea (OSA) severity (as measured by Apnea Hypopnea Index) in predicting
cardiovascular and metabolic aberrations associated with mild-to-moderate obstructive sleep
apnea.


Inclusion Criteria:

- Mild to moderate OSA (5≤ AHI <30)

- BMI ≤ 45

- Age ≥ 18

- Men & Women

Exclusion Criteria:

- AHI ≥ 30

- BMI >45

- Current use of steroids or anti-inflammatory medication

- Diagnosis of insulin dependent diabetes

- Diagnosis of autoimmune disorder

- Shiftwork

- Current use of CPAP
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