A Pilot Study of Optic Nerve Ultrasound Following Cardiopulmonary Bypass

Status:Enrolling by invitation
Conditions:Peripheral Vascular Disease, Cardiology, Cardiology
Therapuetic Areas:Cardiology / Vascular Diseases
Age Range:Any - 18
Start Date:March 2019
End Date:December 2020

Use our guide to learn which trials are right for you!

The purpose of the proposed study is to evaluate the incidence of subtle increases in
intracranial pressure (ICP) following cardiopulmonary bypass (CPB) using optic nerve sheath
diameter (ONSD), measured by non-invasive ultrasound. As direct measurements of ICP are not
feasible following CPB, ONSD will be used as a correlate of ICP. ONSD has been shown to be
effective in the ICU and emergency room setting for detecting increased ICP and is an
accepted standard for such measurements. The primary hypothesis is that changes in ICP occur
following CPB without clinically appreciable signs and symptoms. These changes in ICP will be
reflected by changes in ONSD. If there is a significant incidence of sub-clinical cerebral
edema and increased ICP postoperatively, these findings may impact postoperative hemodynamic
and ventilation goals and techniques.

Inclusion Criteria:

- Patients less than 18 years of age undergoing cardiac bypass.

Exclusion Criteria:
We found this trial at
700 Childrens Drive
Columbus, Ohio 43205
(616) 722-2000
Nationwide Children's Hospital At Nationwide Children’s, we are creating the future of pediatric health care....
Columbus, OH
Click here to add this to my saved trials