The Endocannabinoid System in Human Gestational Tissues in Labor

This is a pilot study to determine the feasibility of identification and quantification of
various components of the endocannabinoid system in the labored versus non-labored
myometrium, placenta and gestational membranes.

Inclusion Criteria:

- Pregnant women ages > 18 years old

- Pregnant women 22 weeks, 0 days through 42 weeks, 0 days gestation undergoing cesarean
section

- Singleton gestation

Exclusion Criteria:

- Cannabinoid use during pregnancy

- Illicit drug use during pregnancy

- Nonsteroidal anti-inflammatory drug use within 7 days of cesarean section

- Maternal comorbidities including pre-existing diabetes, pre-existing hypertension,
hypertensive disorders of pregnancy (preeclampsia, eclampsia), epilepsy currently
being treated with antiepileptic medication, intraamniotic infection

- Uterine abnormalities

- Fetal anomalies

- Drug use or dependency