Interventions for Postoperative Delirium: Biomarker-2 (IPOD-B2)



Status:Recruiting
Conditions:Neurology, Psychiatric
Therapuetic Areas:Neurology, Psychiatry / Psychology
Healthy:No
Age Range:21 - Any
Updated:11/23/2018
Start Date:June 2016
End Date:December 2021
Contact:Heidi L Lindroth, BSN RN
Email:hlindroth@wisc.edu
Phone:608-262-6469

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Interventions for Postoperative Delirium: Biomarker-2 (IPOD-B2) Pilot Study

The IPOD-B2 Study aims to understand the pathogenesis of postoperative delirium in patients
undergoing major surgery. The investigators will identify then correlate soluble biomarkers
in blood and cerebral spinal fluid with changes in High Density-Electroencephalogram.


Inclusion Criteria:

1. Adult (>21 years old)

2. Patients scheduled for an elective open thoracoabdominal aortic aneurysm or TEVAR
(thoracic endovascular aortic/aneurysm repair)

3. Requiring spinal drain for surgery that is predicted to stay in two or more days

4. Willing and able to provide informed consent

Exclusion Criteria:

1. Contraindication for spinal drain

2. Documented history of dementia

3. Unable to communicate with the research staff due to language barriers

4. Individuals who the PI determines are not appropriate for the study such as a history
of appointment cancellations.

5. Pregnant or Nursing

6. Prisoners
We found this trial at
1
site
Madison, Wisconsin 53706
(608) 263-2400
Principal Investigator: Robert D Sanders, MBBS PhD FRCA
Phone: 608-262-6469
University of Wisconsin-Madison In achievement and prestige, the University of Wisconsin-Madison has long been recognized...
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