Solid Tumor Imaging MR‐Linac (STIM Study)
| Status: | Recruiting |
|---|---|
| Conditions: | Cancer, Cancer |
| Therapuetic Areas: | Oncology |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 11/9/2018 |
| Start Date: | October 2, 2017 |
| End Date: | July 1, 2021 |
| Contact: | Medical College of Wisconsin Clinical Cancer Center |
| Email: | cccto@mcw.edu |
| Phone: | 414-805-8900 |
The use of MRI imaging and image fusion in radiation therapy has dramatically increased
during the past decade. However, the existing MRI-imaging protocols, imaging software and
pulse sequences are all optimized for diagnostic purposes. With the introduction of the
MR-linac, there is a critical and imminent need to develop imaging protocols that build and
adapt the existing imaging parameters within the scope of the FDA-approved software to
acquire MRI images that have less geometric distortion and better spatial resolution.
during the past decade. However, the existing MRI-imaging protocols, imaging software and
pulse sequences are all optimized for diagnostic purposes. With the introduction of the
MR-linac, there is a critical and imminent need to develop imaging protocols that build and
adapt the existing imaging parameters within the scope of the FDA-approved software to
acquire MRI images that have less geometric distortion and better spatial resolution.
The objectives of this study are:
1. To evaluate and optimize advanced magnetic resonance (MRI) imaging pulse sequences for
patients undergoing radiation treatment;
2. To investigate the feasibility of using weekly MRI to assess anatomic and functional
treatment responses of tumors and critical organs during radiation therapy (RT), thus
enabling adaptive radiation therapy;
3. To obtain imaging data and clinical data from participants, for additional research
focused on MRI use for radiation therapy, hypothesis‐driven research protocols may
access;
4. To obtain MRI scans from healthy volunteers from the Department of Radiation Oncology.
These scans will be used to optimize scanning parameters for various body sites and to
identify appropriate positioning methods for future patient treatments.
1. To evaluate and optimize advanced magnetic resonance (MRI) imaging pulse sequences for
patients undergoing radiation treatment;
2. To investigate the feasibility of using weekly MRI to assess anatomic and functional
treatment responses of tumors and critical organs during radiation therapy (RT), thus
enabling adaptive radiation therapy;
3. To obtain imaging data and clinical data from participants, for additional research
focused on MRI use for radiation therapy, hypothesis‐driven research protocols may
access;
4. To obtain MRI scans from healthy volunteers from the Department of Radiation Oncology.
These scans will be used to optimize scanning parameters for various body sites and to
identify appropriate positioning methods for future patient treatments.
Inclusion Criteria:
- Cancer patients with any solid tumor type planning to undergo a course of radiation
therapy.
- Healthy volunteers from the Department of Radiation Oncology staff will sign an IRB
approved consent form and complete the MRI eligibility checklist. The MRI scans will
be performed outside normal working hours.
- Ability and willingness to provide written informed consent.
- All subjects (including patients and healthy volunteers) will complete the MRI History
form.
Exclusion Criteria:
- People under 18 years of age.
- Pregnant women.
- People with MRI contraindicated conditions as evaluated during routine MR screening.
We found this trial at
1
site
9200 W Wisconsin Ave
Milwaukee, Wisconsin 53226
Milwaukee, Wisconsin 53226
(414) 805-3666
Phone: 414-805-8900
Froedtert and the Medical College of Wisconsin Froedtert Health combines with the Medical College of...
Click here to add this to my saved trials
