Diode Laser Study for Periodontal Maintenance Patients
| Status: | Completed |
|---|---|
| Conditions: | Dental |
| Therapuetic Areas: | Dental / Maxillofacial Surgery |
| Healthy: | No |
| Age Range: | 30 - Any |
| Updated: | 11/3/2018 |
| Start Date: | May 2010 |
| End Date: | July 2011 |
Adjunctive Non-Surgical Therapy of Inflamed Periodontal Pockets Using Diode Lasers During Maintenance Therapy
This study tries to determine whether the additional use of laser with "cleaning" (known as
scaling and root planning) will result in the reduction of inflammation, reduction of
bleeding upon examination and reduction of pocket depth in patients who are being maintained
on a regular basis but have pocket depths that are ≥5mm with bleeding. When a pocket is
bleeding, it is inflamed. It is usually "cleaned" with periodontal instruments (root-planed)
to establish health. Some research also advocates using laser therapy to treat a bleeding
pocket. Laser therapy is presently being performed in some dental offices and dental
colleges. This research is trying to see if the additional laser therapy is beneficial.
scaling and root planning) will result in the reduction of inflammation, reduction of
bleeding upon examination and reduction of pocket depth in patients who are being maintained
on a regular basis but have pocket depths that are ≥5mm with bleeding. When a pocket is
bleeding, it is inflamed. It is usually "cleaned" with periodontal instruments (root-planed)
to establish health. Some research also advocates using laser therapy to treat a bleeding
pocket. Laser therapy is presently being performed in some dental offices and dental
colleges. This research is trying to see if the additional laser therapy is beneficial.
The purpose of this study is to determine whether the adjunctive use of diode laser with
scaling and root planing is more effective than scaling and root planing alone in clinically
reducing periodontal pocket depth (PD), reducing bleeding on probing (BOP) and gaining of
clinical attachment level (CAL). It also assesses whether diode laser with scaling and root
planing will have an effect on cytokines and inflammatory biomarkers compared to root planing
alone.
Any adult who is currently a routine periodontal maintenance patient and has one or more ≥
5mm pockets with BOP will be invited to participate in the study. If they choose to
participate, they will sign an informed consent. Crevicular fluid samples from each test site
and another non-involved site in the mouth will be collected utilizing the standard protocol
and frozen for later analyses of the presence of certain inflammatory biomarkers (IL-1β).
Baseline data (i.e., PD, CAL, BOP, suppuration, supragingival plaque, subgingival restorative
margins, smoking status) will be collected. The involved teeth will then be randomly treated
with scaling and root-planing with hand instruments and diode laser (test) or scaling and
root-planing with hand instruments alone. The patient will return 3 months later for
follow-up data collection. He/she will then receive his/her regular 3 month maintenance
therapy.
The changes between baseline and 3 months for the clinical parameters and gingival crevicular
fluids' inflammatory biomarkers will be compared between test and control experimental sites.
scaling and root planing is more effective than scaling and root planing alone in clinically
reducing periodontal pocket depth (PD), reducing bleeding on probing (BOP) and gaining of
clinical attachment level (CAL). It also assesses whether diode laser with scaling and root
planing will have an effect on cytokines and inflammatory biomarkers compared to root planing
alone.
Any adult who is currently a routine periodontal maintenance patient and has one or more ≥
5mm pockets with BOP will be invited to participate in the study. If they choose to
participate, they will sign an informed consent. Crevicular fluid samples from each test site
and another non-involved site in the mouth will be collected utilizing the standard protocol
and frozen for later analyses of the presence of certain inflammatory biomarkers (IL-1β).
Baseline data (i.e., PD, CAL, BOP, suppuration, supragingival plaque, subgingival restorative
margins, smoking status) will be collected. The involved teeth will then be randomly treated
with scaling and root-planing with hand instruments and diode laser (test) or scaling and
root-planing with hand instruments alone. The patient will return 3 months later for
follow-up data collection. He/she will then receive his/her regular 3 month maintenance
therapy.
The changes between baseline and 3 months for the clinical parameters and gingival crevicular
fluids' inflammatory biomarkers will be compared between test and control experimental sites.
Inclusion Criteria:
- Any adult periodontal maintenance patient having had chronic periodontitis with last
active therapy at least 3 months prior and with 1 or more sites/subject with ≥5mm
probing depth that have bleeding on probing and/or suppuration. They have signed an
informed consent form to participate in the study.
Exclusion Criteria:
- Subjects who are un-controlled diabetics, use NSAIDS regularly for chronic
disease/pain, used antibiotics for the last 3 months, require antibiotic coverage for
therapy, are pregnant and below age 30.
We found this trial at
1
site
4000 East Campus Loop
Lincoln, Nebraska 68583
Lincoln, Nebraska 68583
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