Urinary Tract Infections Rates Using 50% Dextrose Plus Washout Versus Normal Saline as Cystoscopy Fluid



Status:Recruiting
Conditions:Urology
Therapuetic Areas:Nephrology / Urology
Healthy:No
Age Range:Any
Updated:10/27/2018
Start Date:February 1, 2018
End Date:May 2019
Contact:Heather Crowe
Email:Crowe.Heather1@mayo.edu
Phone:480-342-3987

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Comparison of Urinary Tract Infections Rates Using 50% Dextrose Plus Washout Versus Normal Saline as Cystoscopy Fluid: a Prospective Study

Our study will compare the rates of postoperative urinary tract infections (UTI) between
patients who undergo cystoscopy using 50% dextrose injection plus bladder washout versus
normal saline after hysterectomy for benign indications. Primary outcome will be rates of
urinary tract infections at 6-9 days post-operatively. This will be defined as a urine
culture yielding greater than 100,000 gram-negative colony-forming units per milliliter.

This will be a prospective cohort study of the rate of UTIs after cystoscopic distention
media of normal saline with maximum injection of 40 cc of 50% dextrose plus 300 cc of normal
saline washout versus normal saline after hysterectomy for benign indications.

A pre-operative urine culture will be obtained via mid-stream clean catch prior to
administration of routine pre-operative prophylactic antibiotics.

At 6-9 days post-operatively, a repeat urine culture will be obtained via mid-stream clean
catch. Appropriate treatment will be administered if the urine culture is positive.Primary
outcome will be rates of urinary tract infections at 6-9 days post-operatively. This will be
defined as a urine culture yielding greater than 100,000 gram-negative colony-forming units
per milliliter.

Inclusion Criteria:

- Preoperative scheduling CPT codes for hysterectomy

Exclusion Criteria:

- Discharged home with indwelling foley catheter

- Indwelling foley catheter > 24 hours

- Ureteral injury

- Chronic immunosuppression

- History of diabetes

- Recurrent UTIs (≥2 infections in six months or ≥3 infections in one year)

- Reported Chronic Kidney Disease

- Renal anomalies
We found this trial at
1
site
Scottsdale, Arizona 85259
Principal Investigator: Jeffrey Cornella, MD
Phone: 480-342-3987
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mi
from
Scottsdale, AZ
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