Universal vs. Targeted School Screening for Adolescent Major Depressive Disorder



Status:Enrolling by invitation
Conditions:Depression, Depression, Major Depression Disorder (MDD)
Therapuetic Areas:Psychiatry / Psychology, Pulmonary / Respiratory Diseases
Healthy:No
Age Range:Any
Updated:2/8/2019
Start Date:July 1, 2018
End Date:December 2020

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Randomized Controlled Trial of Universal vs. Targeted School Screening for Adolescent Major Depressive Disorder

The primary goal of the proposed study is to compare the effectiveness of universal school
based screening for adolescent major depressive disorder to the current school process of
targeted screening based on concerning behavior.

The prevalence of annual major depressive disorder (MDD) episodes has increased by greater
than 50% from 2008 to 2015 among US adolescents. Paralleling the rise in MDD, suicide is now
the 2nd leading cause of adolescent deaths. Despite the US Preventive Services Task Force
(USPSTF) 2009 endorsement of universal screening for adolescent MDD in primary care, MDD
screening occurs in less than 2% of office visits.

The primary goal of the proposed study is to compare the effectiveness of universal versus
targeted adolescent MDD screening in a school setting. Universal screening was chosen to be
conducted in schools because, compared to medical settings; schools are more likely to
regularly engage with adolescents.

The hypothesis is that universal school-based screening with the validated Patient Health
Questionnaire (PHQ) will result in increased rates of MDD screening, identification and
treatment engagement. The Penn State team brings a breadth of experience in pediatrics,
community-engaged research, adolescent health, psychiatry and engagement with minority
populations.

Inclusion Criteria:

- Students in grades 9-12 at anticipated 12 public schools in Pennsylvania. HRSA funding
for primarily rural school districts (only Steelton-Highspire is urban). PCORI funding
for urban school districts.

Exclusion Criteria:

- Students whose parents complete the opt-out consent

- Students not enrolled in one of the participating schools

- Students not in grades 9-12

- Students with disabilities that are deemed unable to participate by the school
district
We found this trial at
1
site
Hershey, Pennsylvania 17033
?
mi
from
Hershey, PA
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