The Effect of a Reduced Noise Environment on Induction and Emergence Behavior in Children Undergoing General Anesthesia

Status:Enrolling by invitation
Age Range:2 - 7
Start Date:October 18, 2018
End Date:December 2020

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This project will investigate whether reduction in ambient light and elimination of noise on
induction of anesthesia alters anxiety (modified Yale Preoperative Anxiety Scale or mYPAS) or
compliance (induction compliance checklist or ICC scoring), alters recovery following
emergence using pain scores, analgesic requirements, and emergence delirium (post anesthesia
emergence delirium or PAED), or post-discharge behavior at 1, 7 and 14 days (modified post
hospitalization behaviour questionnaire or PHBQ) in patients who receive anxiolytic
premedication. In addition, the investigators will assess the cumulative level of nose
exposure that patients experience during the perioperative period.

Inclusion Criteria:

- Undergoing general anesthesia for tonsillectomy/adenoidectomy, tympanomastoidectomy,
or general abdominal laparoscopic surgical procedures lasting at least 30 minutes.

- Receiving midazolam prior to the procedure as part of standard of care.

Exclusion Criteria:

- Patients that are taking antidepressant medications, anxiolytic medication, analgesia
medications other than acetaminophen or NSAIDs.

- Allergy to midazolam.

- History of emergence delirium.

- Cardiac disease, other than functional heart murmurs.

- Developmental delays.

- Parent refusal of midazolam for standard clinical care.
We found this trial at
700 Childrens Drive
Columbus, Ohio 43205
(616) 722-2000
Nationwide Children's Hospital At Nationwide Children’s, we are creating the future of pediatric health care....
Columbus, OH
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