Prospective Study of Methicillin-Resistant Staphylococcus Aureus (MRSA) Among HIV-Infected Persons



Status:Completed
Conditions:Infectious Disease, HIV / AIDS, Hospital
Therapuetic Areas:Immunology / Infectious Diseases, Other
Healthy:No
Age Range:18 - Any
Updated:8/18/2018
Start Date:May 2007
End Date:October 2017

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Prospective Study on the Incidence, Predictors, and Characteristics of Methicillin-Resistant Staphylococcus Aureus Infections and a Randomized, Double-Blind Study on Decolonization Procedures for Prevention of MRSA Infections Among HIV-Infected Persons

This study will prospectively evaluate the prevalence and incidence (over a two year period)
of MRSA colonization and infection among HIV-infected military beneficiaries to determine
predictors for the development of MRSA colonization and infection. This study will also
investigate the utility of decolonization procedures for clearance of MRSA carriage and
prevention of MRSA infections. Finally, the molecular characteristics and the antimicrobial
sensitivities of isolates in this population will be determined.


Inclusion Criteria:

- Adults (at least 18 years of age) who are HIV positive by a reactive screening (ELISA,
EIA) and a confirmatory test (Western blot) and who are able to attend the study
visits which are every 6 months (+/- 2 months), at the minimum

Exclusion Criteria:

- Known allergy to mupirocin (Bactroban®) nasal ointment or hexachlorophene (pHisoHex®)
soaps or constituents of these products.

- Age less than 18 years.

- Inability to remain in the study for the two year duration.

- Pregnant or breastfeeding females.

- Females who intend to become pregnant during the two year study time period.

- Persons who are healthcare providers with direct patient contact.
We found this trial at
4
sites
620 John Paul Jones Cir
Portsmouth, Virginia 23708
(757) 953-5008
Naval Medical Center - Portsmouth Naval Medical Center Portsmouth, Virginia has proudly served the military...
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Portsmouth, VA
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8901 Rockville Pike
Bethesda, Maryland 20889
(301) 295-4000
Walter Reed National Military Medical Center The Walter Reed National Military Medical Center is one...
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Bethesda, MD
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3551 Roger Brooke Drive
San Antonio, Texas 78236
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San Antonio, TX
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34800 Bob Wilson Drive
San Diego, California 92134
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San Diego, CA
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